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dc.contributor.authorEvans, Josieen_UK
dc.contributor.authorMacGregor, Ailsa Men_UK
dc.contributor.authorMurray, Frank Een_UK
dc.contributor.authorVaidya, Kishor Sen_UK
dc.contributor.authorMorris, Andrew Den_UK
dc.contributor.authorMacDonald, Thomas Men_UK
dc.description.abstractBackground: A recent case-control study reported an association between non-steroidal antiinflammatory drug (NSAID) use and acute appendicitis. This association was investigated in a case-control study of patients, aged 30 years and over, admitted as an emergency to hospitals in Tayside between 1989 and 1992, who had appendicectomy for acute appendicitis. Methods: A record-linkage database containing records of dispensed prescriptions and hospital admissions was used. A total of 223 patients were identified. The medical records of 161 were checked, of which 138 were valid cases, and information on white cell count and NSAID exposure was recorded. Community and hospital controls were generated. Results: Some 9.0 per cent of patients were prescribed NSAIDs within 90 days of hospitalization, compared with 7.6 per cent of community controls and 11.5 per cent of hospital controls. The odds ratio was 1.21 (95 per cent confidence interval 0.73-2.01) and 0.75 (0.43-1.32) respectively. There was no significant difference in white cell count between exposed and non-exposed cases. No increased risk of appendicectomy was associated with aspirin use: odds ratio 1.67 (052-5.30) and 0.37 (0.1 2-1.13) using community and hospital controls respectively. Conclusion: Appendicectomy for acute appendicitis is not associated with increased prior use of NSAIDs.en_UK
dc.publisherJohn Wiley and Sons for the British Journal of Surgery Societyen_UK
dc.relationEvans J, MacGregor AM, Murray FE, Vaidya KS, Morris AD & MacDonald TM (1997) No association between non-steroidal anti-inflammatory drugs and acute appendicitis in a case-control study. British Journal of Surgery, 84 (3), pp. 372-374.;
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.titleNo association between non-steroidal anti-inflammatory drugs and acute appendicitis in a case-control studyen_UK
dc.typeJournal Articleen_UK
dc.rights.embargoreason[Evans_1997_No_association_between_non-steroidal_anti-inflammatory_drugs.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.citation.jtitleBritish Journal of Surgeryen_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.affiliationHealth Sciences Research - Stirling - LEGACYen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationNinewells Hospital & Medical Schoolen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationNinewells Hospital & Medical Schoolen_UK
rioxxterms.typeJournal Article/Reviewen_UK
local.rioxx.authorEvans, Josie|0000-0001-6672-7876en_UK
local.rioxx.authorMacGregor, Ailsa M|en_UK
local.rioxx.authorMurray, Frank E|en_UK
local.rioxx.authorVaidya, Kishor S|en_UK
local.rioxx.authorMorris, Andrew D|en_UK
local.rioxx.authorMacDonald, Thomas M|en_UK
local.rioxx.projectInternal Project|University of Stirling|
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles

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