Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/8782
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dc.contributor.authorMcMahon, Alexen_UK
dc.contributor.authorEvans, Josieen_UK
dc.contributor.authorWhite, Gen_UK
dc.contributor.authorMurray, Frank Een_UK
dc.contributor.authorMcGilchrist, Mark Men_UK
dc.contributor.authorMcDevitt, Denis Gen_UK
dc.contributor.authorMacDonald, Thomas Men_UK
dc.date.accessioned2014-09-12T12:51:33Z-
dc.date.available2014-09-12T12:51:33Zen_UK
dc.date.issued1997-03en_UK
dc.identifier.urihttp://hdl.handle.net/1893/8782-
dc.description.abstractThis cohort study examined the relationship between newly prescribed NSAIDs (none in the previous six months) and upper gastrointestinal hemorrhage and perforation in Tayside, Scotland. Exposure was classified by prescription duration. The study population consisted of the population of Tayside. A Comparator Group was chosen at random (within age and sex strata). Two hundred re-sampled comparator groups were created. Statistical analyses were carried out by Poisson regression (repeated for each of the re-samples). The analyses controlled for age, sex, prior hospitalization for upper gastrointestinal events, prior endoscopy, and the use of ulcer healing drugs. There were 78,191 subjects in the NSAID group, and 78,207 in each of the comparator groups. The increased risk with NSAIDs was only apparent for subjects without a history of upper gastrointestinal events; univariate rate ratio = 2.76 (1.90, 4.01). The final, re-sampled estimate of NSAID risk was rate ratio = 2.48 (1.87, 3.29).en_UK
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.relationMcMahon A, Evans J, White G, Murray FE, McGilchrist MM, McDevitt DG & MacDonald TM (1997) A cohort study (with re-sampled comparator groups) to measure the association between new NSAID prescribing and upper gastrointestinal hemorrhage and perforation. Journal of Clinical Epidemiology, 50 (3), pp. 351-356. https://doi.org/10.1016/S0895-4356%2896%2900361-7en_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.subjectCohorten_UK
dc.subjectEpidemiologyen_UK
dc.subjectRe-samplingen_UK
dc.subjectNSAIDen_UK
dc.subjectHemorrhageen_UK
dc.subjectPerforationen_UK
dc.titleA cohort study (with re-sampled comparator groups) to measure the association between new NSAID prescribing and upper gastrointestinal hemorrhage and perforationen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-04-01en_UK
dc.rights.embargoreason[Evans_1997_A_Cohort_Study.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.identifier.doi10.1016/S0895-4356(96)00361-7en_UK
dc.citation.jtitleJournal of Clinical Epidemiologyen_UK
dc.citation.issn0895-4356en_UK
dc.citation.volume50en_UK
dc.citation.issue3en_UK
dc.citation.spage351en_UK
dc.citation.epage356en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emailjosie.evans@stir.ac.uken_UK
dc.citation.date15/12/1997en_UK
dc.contributor.affiliationASS Management and Support Team - LEGACYen_UK
dc.contributor.affiliationHealth Sciences Research - Stirling - LEGACYen_UK
dc.contributor.affiliationNinewells Hospital & Medical Schoolen_UK
dc.contributor.affiliationNinewells Hospital & Medical Schoolen_UK
dc.contributor.affiliationNinewells Hospital & Medical Schoolen_UK
dc.contributor.affiliationNinewells Hospital & Medical Schoolen_UK
dc.contributor.affiliationNinewells Hospital & Medical Schoolen_UK
dc.identifier.isiWOS:A1997WQ59200018en_UK
dc.identifier.wtid781694en_UK
dc.contributor.orcid0000-0001-6672-7876en_UK
dc.date.filedepositdate2012-09-03en_UK
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles

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