Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/6520
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dc.contributor.authorHunter, Angus-
dc.contributor.authorGibson, Alan St Clair-
dc.contributor.authorDerman, Wayne E-
dc.contributor.authorLambert, Michael-
dc.contributor.authorDennis, Stephen C-
dc.contributor.authorNoakes, Timothy D-
dc.date.accessioned2016-09-06T03:12:45Z-
dc.date.available2016-09-06T03:12:45Z-
dc.date.issued2002-
dc.identifier.urihttp://hdl.handle.net/1893/6520-
dc.description.abstractThis study analysed the effect of selective b1- blockade on neuromuscular recruitment characteristics during progressive endurance exercise. Ten healthy subjects ingested a selective b1-blocker, acebutolol (200 mg b.d.), for 7 days (for one of two cycling trials), with a 10-day wash-out period between trials. On the last day of acebutolol ingestion subjects performed three successive 15-min rides at 30%, 50% and 70% of their peak power output and then cycled at increasing (15 W min-1) work rates to exhaustion. Force output, heart rate, submaximal V_O2, rate of perceived exertion (RPE), electromyographic (EMG) data and blood lactate were captured during the cycling activity. Peak work rate [270 (111) W vs 197 (75) W, CON vs BETA, P<0.01], time to exhaustion [49.7 (23.2) min vs 40.3 (23.7) min, CON vs BETA, P <0.05] and heart rate [mean, for the full ride 135.5 (38.3) beats min-1 vs 111.5 (30.0) beats min-1 CON vs BETA, P <0.05] were significantly lower for the group who ingested b1-blockade (BETA) compared to the control group (CON). Although not significant, submaximal V_O2 was reduced in BETA during the ride, while RPE was significantly higher during the ride for BETA (P <0.01). Mean integrated electromyography was higher in the BETA group although these differences were not significant. Mean power frequency values of the BETA group showed a significant (P <0.05) shift to the upper end of the spectrum in comparison to the control group. Lactate values [11.7 (3.5) mmol.l-1 vs 7.1 (4.1) mmol.l-1 CON vs BETA] were significantly lower (P <0.05) at exhaustion in BETA. Significant reductions in cycling performance were found when subjects ingested b1- blockers. This study has shown significant shifts to the upper end of the EMG frequency spectrum after b1- blocker ingestion, which could be caused by a change in neuromuscular recruitment strategy to compensate for the impaired submaximal exercise performance.en_UK
dc.language.isoen-
dc.publisherSpringer Verlag-
dc.relationHunter A, Gibson ASC, Derman WE, Lambert M, Dennis SC & Noakes TD (2002) The effect of selective beta1-blockade on EMG signal characteristics during progressive endurance exercise, European Journal of Applied Physiology, 88 (3), pp. 275-281.-
dc.rightsPublished in European Journal of Applied Physiology and Occupational Physiology by Spriger Verlag. The original publication is available at www.springerlink.com-
dc.subjectβ1-Blockadeen_UK
dc.subjectFatigueen_UK
dc.subjectIntegrated electromyographyen_UK
dc.subjectMean power frequency spectrumen_UK
dc.titleThe effect of selective beta1-blockade on EMG signal characteristics during progressive endurance exerciseen_UK
dc.typeJournal Articleen_UK
dc.identifier.doihttp://dx.doi.org/10.1007/s00421-002-0710-5-
dc.citation.jtitleEuropean Journal of Applied Physiology-
dc.citation.issn1439-6319-
dc.citation.volume88-
dc.citation.issue3-
dc.citation.spage275-
dc.citation.epage281-
dc.citation.publicationstatusPublished-
dc.citation.peerreviewedRefereed-
dc.type.statusPost-print (author final draft post-refereeing)-
dc.identifier.urlhttp://www.scopus.com/inward/record.url?partnerID=yv4JPVwI&eid=2-s2.0-0036886635&md5=7ecdf82d22298ca66fbeb434cf69c9c5-
dc.author.emaila.m.hunter1@stir.ac.uk-
dc.citation.date17/10/2002-
dc.contributor.affiliationSport-
dc.contributor.affiliationUniversity of Cape Town-
dc.contributor.affiliationUniversity of Cape Town-
dc.contributor.affiliationUniversity of Cape Town-
dc.contributor.affiliationUniversity of Cape Town-
dc.contributor.affiliationUniversity of Cape Town-
dc.identifier.isi000180100400010-
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles

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