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dc.contributor.authorDe Nys, Lenen_UK
dc.contributor.authorOfosu, Esther F.en_UK
dc.contributor.authorRyde, Gemma C.en_UK
dc.contributor.authorConnelly, Jennien_UK
dc.contributor.authorWhittaker, Anna C.en_UK
dc.description.abstractAge-related changes affect the ratio between two steroid hormones of the hypothalamic-pituitary-adrenal axis, cortisol and dehydroepiandrosterone (sulfate) (DHEA[S]). Physical activity (PA) may buffer the effects of chronic stress and counteract the aging decline of DHEA(S). Therefore, a systematic review was conducted to understand how PA influences physiological markers of cortisol and/or DHEA(S) and whether there is a difference in observational associations or experimental effects in older adults aged 65 years and older. A narrative synthesis was performed on nine observational studies, and meta-analyses were performed on 22 randomized controlled trials. There was low- to moderate-quality evidence that regular PA beneficially reduces cortisol and increases DHEA(S) levels. Subgroup analyses showed no clinically important differences between men and women, different exercise modalities, or health states. The findings cautiously suggest that regular PA of older adults’ own choice that they find enjoyable could be recommended to improve cortisol and/or DHEA(S) levels.en_UK
dc.publisherHuman Kineticsen_UK
dc.relationDe Nys L, Ofosu EF, Ryde GC, Connelly J & Whittaker AC (2022) Physical Activity Influences Cortisol and Dehydroepiandrosterone (Sulfate) Levels in Older Adults: A Systematic Review and Meta-Analysis. Journal of Aging and Physical Activity.
dc.rights[JAPA_Main Document.pdf] Accepted author manuscript version reprinted, by permission, from Journal of Aging and Physical Activity, 2022, © Human Kinetics, Inc.en_UK
dc.rights[DeNys-etal-JAPA-2022.pdf] The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.subjectphysical fitnessen_UK
dc.subjecthealthy agingen_UK
dc.subjectchronic stressen_UK
dc.subjectaged 65 and overen_UK
dc.titlePhysical Activity Influences Cortisol and Dehydroepiandrosterone (Sulfate) Levels in Older Adults: A Systematic Review and Meta-Analysisen_UK
dc.typeJournal Articleen_UK
dc.rights.embargoreason[DeNys-etal-JAPA-2022.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.citation.jtitleJournal of Aging and Physical Activityen_UK
dc.type.statusVoR - Version of Recorden_UK
dc.type.statusAM - Accepted Manuscripten_UK
dc.description.notesOutput Status: Forthcoming/Available Onlineen_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
local.rioxx.authorDe Nys, Len|en_UK
local.rioxx.authorOfosu, Esther F.|en_UK
local.rioxx.authorRyde, Gemma C.|en_UK
local.rioxx.authorConnelly, Jenni|0000-0002-2517-9399en_UK
local.rioxx.authorWhittaker, Anna C.|0000-0002-5461-0598en_UK
local.rioxx.projectInternal Project|University of Stirling|
local.rioxx.filenameJAPA_Main Document.pdfen_UK
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles

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