Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/34462
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dc.contributor.authorDoody, Paulen_UK
dc.contributor.authorAsamane, Evans Aen_UK
dc.contributor.authorAunger, Justin Aen_UK
dc.contributor.authorSwales, Bridgitteen_UK
dc.contributor.authorLord, Janet Men_UK
dc.contributor.authorGreig, Carolyn Aen_UK
dc.contributor.authorWhittaker, Anna Cen_UK
dc.date.accessioned2022-06-29T00:01:10Z-
dc.date.available2022-06-29T00:01:10Z-
dc.date.issued2022-09en_UK
dc.identifier.other101666en_UK
dc.identifier.urihttp://hdl.handle.net/1893/34462-
dc.description.abstractBackground Frailty is a common and clinically significant condition among geriatric populations. Although well-evidenced pooled estimates of the prevalence of frailty exist within various settings and populations, presently there are none assessing the overall prevalence of frailty among geriatric hospital inpatients. The purpose of this review was to systematically search and analyse the prevalence of frailty among geriatric hospital inpatients within the literature and examine its associations with national economic indicators. Methods Systematic searches were conducted on Ovid, Web of Science, Scopus, CINAHL Plus, and the Cochrane Library, encompassing all literature published prior to 22 November 2018, supplemented with manual reference searches. Included studies utilised a validated operational definition of frailty, reported the prevalence of frailty, had a minimum age ≥ 65 years, attempted to assess the whole ward/clinical population, and occurred among hospital inpatients. Two reviewers independently extracted data and assessed study quality. Results Ninety-six studies with a pooled sample of 467,779 geriatric hospital inpatients were included. The median critical appraisal score was 8/9 (range 7–9). The pooled prevalence of frailty, and pre-frailty, among geriatric hospital inpatients was 47.4% (95% CI 43.7–51.1%), and 25.8% (95% CI 22.0–29.6%), respectively. Significant differences were observed in the prevalence of frailty stratified by age, prevalent morbidity, ward type, clinical population, and operational definition. No significant differences were observed in stratified analyses by sex or continent, or significant associations between the prevalence of frailty and economic indicators. Conclusions Frailty is highly prevalent among geriatric hospital inpatients. High heterogeneity exists within this setting based on various clinical and demographic characteristics. Pooled estimates reported in this review place the prevalence of frailty among geriatric hospital inpatients between that reported for community-dwelling older adults and older adults in nursing homes, outlining an increase in the relative prevalence of frailty with progression through the healthcare system.en_UK
dc.language.isoenen_UK
dc.publisherElsevier BVen_UK
dc.relationDoody P, Asamane EA, Aunger JA, Swales B, Lord JM, Greig CA & Whittaker AC (2022) The prevalence of frailty and pre-frailty among geriatric hospital inpatients and its association with economic prosperity and healthcare expenditure: A systematic review and meta-analysis of 467,779 geriatric hospital inpatients. Ageing Research Reviews, 80, Art. No.: 101666. https://doi.org/10.1016/j.arr.2022.101666en_UK
dc.rightsThis is an open access article distributed under the terms of the Creative Commons CC-BY license (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You are not required to obtain permission to reuse this article.en_UK
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_UK
dc.subjectHealth economicsen_UK
dc.subjectFrailtyen_UK
dc.subjectHospitalen_UK
dc.subjectInpatientsen_UK
dc.subjectOlder adultsen_UK
dc.subjectPrevalenceen_UK
dc.titleThe prevalence of frailty and pre-frailty among geriatric hospital inpatients and its association with economic prosperity and healthcare expenditure: A systematic review and meta-analysis of 467,779 geriatric hospital inpatientsen_UK
dc.typeJournal Articleen_UK
dc.identifier.doi10.1016/j.arr.2022.101666en_UK
dc.identifier.pmid35697143en_UK
dc.citation.jtitleAgeing Research Reviewsen_UK
dc.citation.issn1568-1637en_UK
dc.citation.volume80en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.funderEuropean Commission (Horizon 2020)en_UK
dc.author.emaila.c.whittaker@stir.ac.uken_UK
dc.citation.date11/06/2022en_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationSporten_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationSporten_UK
dc.identifier.scopusid2-s2.0-85133735206en_UK
dc.identifier.wtid1824164en_UK
dc.contributor.orcid0000-0002-5461-0598en_UK
dc.date.accepted2022-06-06en_UK
dcterms.dateAccepted2022-06-06en_UK
dc.date.filedepositdate2022-06-23en_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorDoody, Paul|en_UK
local.rioxx.authorAsamane, Evans A|en_UK
local.rioxx.authorAunger, Justin A|en_UK
local.rioxx.authorSwales, Bridgitte|en_UK
local.rioxx.authorLord, Janet M|en_UK
local.rioxx.authorGreig, Carolyn A|en_UK
local.rioxx.authorWhittaker, Anna C|0000-0002-5461-0598en_UK
local.rioxx.projectProject ID unknown|European Commission (Horizon 2020)|en_UK
local.rioxx.freetoreaddate2022-06-28en_UK
local.rioxx.licencehttp://creativecommons.org/licenses/by/4.0/|2022-06-28|en_UK
local.rioxx.filename1-s2.0-S1568163722001088-main.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source1568-1637en_UK
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