Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/32791
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dc.contributor.authorKhanfer, Riyaden_UK
dc.contributor.authorPhillips, Anna Cen_UK
dc.contributor.authorCarroll, Douglasen_UK
dc.contributor.authorLord, Janeten_UK
dc.date.accessioned2021-06-26T00:04:37Z-
dc.date.available2021-06-26T00:04:37Z-
dc.date.issued2010-09en_UK
dc.identifier.urihttp://hdl.handle.net/1893/32791-
dc.description.abstractObjective: To examine the effects of an acute laboratory psychological stress task on neutrophil function, specifically phagocytosis of Escherichia coli and stimulated superoxide production in human neutrophils. There is mounting evidence that acute stress is associated with short-term increases in a number of immune indices. Methods: Participants were 40 (n = 20 females) university students (mean age, 25.9 ± 4.56 years). Blood samples to determine neutrophil function by flow cytometry were taken at the end of resting baseline, during an acute stress task, and during recovery. The stress task was a 10-minute time-pressured mental arithmetic challenge with social evaluation. Results: There was an acute increase in phagocytic ability, p = .047, η2p = 0.076, and a reduction of superoxide production, p = .026, η2p = 0.101, associated with the stress task relative to baseline. Conclusion: These findings suggest that neutrophil bactericidal function may be sensitive to mental challenge tasks that provoke acute psychological stress. Further research is needed to replicate the observed psychological stress-induced changes in neutrophil function.en_UK
dc.language.isoenen_UK
dc.publisherLippincott, Williams & Wilkinsen_UK
dc.relationKhanfer R, Phillips AC, Carroll D & Lord J (2010) Altered human neutrophil function in response to acute psychological stress.. Psychosomatic Medicine, 72 (7), pp. 636-640. https://doi.org/10.1097/PSY.0b013e3181e7fae8en_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.rights.urihttp://www.rioxx.net/licenses/under-embargo-all-rights-reserveden_UK
dc.subjectacute psychological stressen_UK
dc.subjectneutrophilen_UK
dc.subjectphagocytosisen_UK
dc.subjectsuperoxide productionen_UK
dc.titleAltered human neutrophil function in response to acute psychological stress.en_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31en_UK
dc.rights.embargoreason[Acute stress young.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.identifier.doi10.1097/PSY.0b013e3181e7fae8en_UK
dc.identifier.pmid20562369en_UK
dc.citation.jtitlePsychosomatic Medicineen_UK
dc.citation.issn1534-7796en_UK
dc.citation.issn0033-3174en_UK
dc.citation.volume72en_UK
dc.citation.issue7en_UK
dc.citation.spage636en_UK
dc.citation.epage640en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.funderUniversity of Birminghamen_UK
dc.author.emaila.c.whittaker@stir.ac.uken_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.identifier.scopusid2-s2.0-77957721334en_UK
dc.identifier.wtid1476416en_UK
dc.contributor.orcid0000-0002-5461-0598en_UK
dc.date.accepted2010-07-01en_UK
dcterms.dateAccepted2010-07-01en_UK
dc.date.filedepositdate2019-11-05en_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorKhanfer, Riyad|en_UK
local.rioxx.authorPhillips, Anna C|0000-0002-5461-0598en_UK
local.rioxx.authorCarroll, Douglas|en_UK
local.rioxx.authorLord, Janet|en_UK
local.rioxx.projectProject ID unknown|University of Birmingham|http://dx.doi.org/10.13039/501100000855en_UK
local.rioxx.freetoreaddate2260-07-01en_UK
local.rioxx.licencehttp://www.rioxx.net/licenses/under-embargo-all-rights-reserved||en_UK
local.rioxx.filenameAcute stress young.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source1534-7796en_UK
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