|Appears in Collections:||Faculty of Health Sciences and Sport Journal Articles|
|Peer Review Status:||Refereed|
|Title:||A statistical and biological response to an informatics appraisal of healthy aging gene signatures|
|Author(s):||Timmons, James A|
Gallagher, Iain J
Kraus, William E
Atherton, Philip J
|Citation:||Timmons JA, Gallagher IJ, Sood S, Phillips B, Crossland H, Howard R, Kraus WE & Atherton PJ (2019) A statistical and biological response to an informatics appraisal of healthy aging gene signatures. Genome Biology, 20 (1), Art. No.: 152. https://doi.org/10.1186/s13059-019-1734-z|
|Abstract:||Jacob and Speed did not identify even a single example of a ‘150-gene-set’ that was statistically significant at classifying Alzheimer’s disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings.|
|Rights:||© 2019 BioMed Central Ltd unless otherwise stated. Part of Springer Nature. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.|
|s13059-019-1734-z.pdf||Fulltext - Published Version||717.68 kB||Adobe PDF||View/Open|
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