Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/29440
Appears in Collections:Faculty of Health Sciences and Sport eTheses
Title: Prevention of type 2 diabetes in high risk groups: epidemiology, progression rates and patient views and experiences.
Author(s): Eades, Claire Elizabeth
Supervisor(s): Evans, J
France, E
Keywords: Impaired glucose regulation
Impaired glucose tolerance
Impaired fasting glucose
Gestational diabetes
Type 2 diabetes
Prevention
Prevalence
Patient views
Illness perceptions
Issue Date: Nov-2018
Publisher: University of Stirling
Citation: Eades, C., France, E. and Evans, J.M.M. (2016) Prevalence of impaired glucose regulation: A meta-analysis. European Journal of Public Health, 26 (4), pp. 699-706. https://doi.org/10.1093/eurpub/ckw085
Eades, C., Cameron, D. and Evans, J.M.M. (2017) Prevalence of gestational diabetes in Europe: a meta-analysis. Diabetes Research and Clinical Practice, 129, pp. 173-181. https://doi.org/10.1016/j.diabres.2017.03.030
Eades, C., Leese, G.P. and Evans, J.M.M. (2014) Incidence of impaired glucose regulation and progression to type 2 diabetes mellitus in the Tayside region of Scotland. Diabetes Research and Clinical Practice, 104 (1), pp. e16-e19. https://doi.org/10.1016/j.diabres.2014.01.012
Eades, C., Styles, M., Leese, G.P., Cheyne, H. and Evans, J.M.M. (2015) Progression from gestational diabetes to type 2 diabetes in one region of Scotland: an observational follow up study. BMC Pregnancy and Childbirth, 15, 11. Available: https://doi.org/10.1186/s12884-015-0457-8 [Accessed 1 November 2018].
Eades, C., France, E. and Evans, J.M.M. (2018) Postnatal experiences, knowledge and perceptions of women with gestational diabetes. Diabetic Medicine, 35 (4), pp. 519-529. https://doi.org/10.1111/dme.13580
Abstract: Background: People with gestational diabetes mellitus (GDM) and impaired glucose regulation (IGR) are at increased risk of developing type 2 diabetes but lifestyle change can help to delay or prevent type 2 diabetes in these groups. Aims: This thesis comprises five publications which inform the development of lifestyle interventions for people with IGR and GDM by describing the epidemiology, progression to type 2 diabetes, and patient views and perceptions associated with these conditions. Methods: Publications one and two used systematic review and meta-analysis methods to describe the prevalence of IGR and GDM in Europe. A retrospective cohort design utilising routinely collected health care data from one region in Scotland was used in publications three and four to describe the incidence of IGR, and the progression from GDM and IGR to type 2 diabetes. Publication five explored women’s perceptions and experiences of GDM using semi-structured interviews informed by behaviour change theory. Results: Mean prevalence of IGR and GDM in developed Europe was 22.3% and 5.4% respectively. Rates of progression to type 2 diabetes were 9% in a mean time of 34 months for IGR and 25% in a mean time of eight years for GDM. Older people with IGR living in deprived areas and women with GDM who were overweight and with higher fasting plasma glucose levels were at most risk of developing type 2 diabetes. Publication five highlighted how perceptions about the consequences of GDM and timeline and consequences of type 2 diabetes may be linked to the lifestyle change women make after diagnosis of GDM and their lack of success in maintaining these changes postnatally. Conclusions: This thesis provides a clear understanding of the prevalence of IGR and GDM, rates of progression to type 2 diabetes, and patient views and perceptions on which to base intervention planning and health care delivery.
Type: Thesis or Dissertation
URI: http://hdl.handle.net/1893/29440

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