Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/26936
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles
Peer Review Status: Refereed
Title: Which measures of cigarette dependence are predictors of smoking cessation during pregnancy? Analysis of data from a randomized controlled trial
Author(s): Riaz, Muhammad
Lewis, Sarah
Coleman, Tim
Aveyard, Paul
West, Robert
Naughton, Felix
Ussher, Michael
Contact Email: michael.ussher@stir.ac.uk
Keywords: Cigarette dependence measures
physical activity
predictors
pregnancy
randomised control trial
secondary analysis
smoking cessation
Issue Date: Sep-2016
Citation: Riaz M, Lewis S, Coleman T, Aveyard P, West R, Naughton F & Ussher M (2016) Which measures of cigarette dependence are predictors of smoking cessation during pregnancy? Analysis of data from a randomized controlled trial, Addiction, 111 (9), pp. 1656-1665.
Abstract: Aims: To examine the ability of different common measures of cigarette dependence to predict smoking cessation during pregnancy.  Design: Secondary analysis of data from a parallel-group randomized controlled trial of physical activity for smoking cessation. The outcomes were biochemically validated smoking abstinence at 4weeks post-quit and end-of pregnancy.  Setting: Women identified as smokers in antenatal clinics in 13 hospital trusts predominantly in southern England, who were recruited to a smoking cessation trial. Participants: Of 789 pregnant smokers recruited, 784 were included in the analysis. Measurements: Using random-effect logistic regression models, we analysed the effects of baseline measures of cigarette dependence, including numbers of cigarettes smoked daily, Fagerstrom Test of Cigarette Dependence (FTCD) score, the two FTCD subscales of Heaviness of Smoking Index (HSI) and non-Heaviness of Smoking Index (non-HSI), expired carbon monoxide (CO) level and urges to smoke (strength and frequency) on smoking cessation. Associations were adjusted for significant socio-demographic/health behaviour predictors and trial variables, and area under the receiver operating characteristic (ROC) curve was used to determine the predictive ability of the model for each measure of dependence.  Findings: All the dependence variables predicted abstinence at 4weeks and end-of-pregnancy. At 4weeks, the adjusted odds ratio (OR) (95% confidence interval) for a unit standard deviation increase in FTCD was 0.59 (0.47-0.74), expired CO=0.54 (0.41-0.71), number of cigarettes smoked per day 0.65 (0.51-0.84) and frequency of urges to smoke 0.79 (0.63-0.98); at end-of-pregnancy they were: 0.60 (0.45-0.81), 0.55 (0.37-0.80), 0.70 (0.49-0.98) and 0.69 (0.51-0.94), respectively. HSI and non-HSI exhibited similar results to the full FTCD.  Conclusions: Four common measures of dependence, including number of cigarettes smoked per day, scores for Fagerstrom Test of Cigarette Dependence and frequency of urges and level of expired CO, all predicted smoking abstinence in the short term during pregnancy and at end-of-pregnancy with very similar predictive validity.
DOI Link: http://dx.doi.org/10.1111/add.13395
Rights: © 2016 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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