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Appears in Collections:Faculty of Health Sciences and Sport Journal Articles
Peer Review Status: Refereed
Title: Molecular studies of exercise, skeletal muscle, and ageing [version 1; referees: 2 approved]
Author(s): Timmons, James A
Gallagher, Iain J
Issue Date: 2-Jun-2016
Date Deposited: 10-Mar-2017
Citation: Timmons JA & Gallagher IJ (2016) Molecular studies of exercise, skeletal muscle, and ageing [version 1; referees: 2 approved]. F1000Research, 5 (F1000 Faculty Rev), Art. No.: 1087.
Abstract: The purpose of an F1000 review is to reflect on the bigger picture, exploring controversies and new concepts as well as providing opinion as to what is limiting progress in a particular field. We reviewed about 200 titles published in 2015 that included reference to ‘skeletal muscle, exercise, and ageing’ with the aim of identifying key articles that help progress our understanding or research capacity while identifying methodological issues which represent, in our opinion, major barriers to progress. Loss of neuromuscular function with chronological age impacts on both health and quality of life. We prioritised articles that studied human skeletal muscle within the context of age or exercise and identified new molecular observations that may explain how muscle responds to exercise or age. An important aspect of this short review is perspective: providing a view on the likely ‘size effect’ of a potential mechanism on physiological capacity or ageing.
DOI Link: 10.12688/F1000RESEARCH.8255.1
Rights: © 2016 Timmons JA and Gallagher IJ. This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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