Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/24901
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dc.contributor.authorZwarenstein, Merricken_UK
dc.contributor.authorTreweek, Shaunen_UK
dc.contributor.authorLoudon, Kirstyen_UK
dc.date.accessioned2018-04-05T22:19:10Z-
dc.date.available2018-04-05T22:19:10Z-
dc.date.issued2017-04-30en_UK
dc.identifier.urihttp://hdl.handle.net/1893/24901-
dc.description.abstractFirst paragraph: We appreciate the efforts of the editors of the Journal of Clinical Epidemiology to provide a forum for discussion of pragmatismi in randomized trials (RCTs), with many items in recent years, including three in this issue by Dekkers et al ii, Zuidegeest et al. iii and Riddle iv. We are encouraged that these three authors agree on the importance of pragmatism and the relevance of PRECIS-2 to RCT designv, our tool to promote better matching of the choices made during design with the intended use of that trial’s results. We thank them for their insightful comments relating to the varied meanings of generalizability, and the relationship between pragmatic and explanatory characteristics and internal validity and applicability (which we use as a synonym for generalizability) of trial results, to which we respond below.en_UK
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.relationZwarenstein M, Treweek S & Loudon K (2017) PRECIS-2 helps researchers design more applicable RCTs while CONSORT Extension for Pragmatic Trials helps knowledge users decide whether to apply them [Commentary on: O.M. Dekkers, P.M. Bossuytd, J.P. Vandenbroucke, How trial results are intended to be used: is PRECIS-2 a step forward? J Clin Epidemiol, 84 (2017), pp. 25–26. M.G. Zuidgeest, I. Goetz, D.E. Grobbee, PRECIS-2 in perspective: what's next for pragmatic trials? J Clin Epidemiol, 84 (2017), pp. 22–24. D.L. Riddle, Consequences of randomized clinical trial design decisions need to be clarified. J Clin Epidemiol, 77 (2016), pp. 13–14.] , Journal of Clinical Epidemiology, 84, pp. 27-29. https://doi.org/10.1016/j.jclinepi.2016.10.010.en_UK
dc.relation.isbasedonO.M. Dekkers, P.M. Bossuytd, J.P. Vandenbroucke, How trial results are intended to be used: is PRECIS-2 a step forward? J Clin Epidemiol, 84 (2017), pp. 25–26. M.G. Zuidgeest, I. Goetz, D.E. Grobbee, PRECIS-2 in perspective: what's next for pragmatic trials? J Clin Epidemiol, 84 (2017), pp. 22–24. D.L. Riddle, Consequences of randomized clinical trial design decisions need to be clarified. J Clin Epidemiol, 77 (2016), pp. 13–14.en_UK
dc.rightsThis item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. Accepted refereed manuscript of: Zwarenstein M, Treweek S & Loudon K (2017) PRECIS-2 helps researchers design more applicable RCTs while CONSORT Extension for Pragmatic Trials helps knowledge users decide whether to apply them. Journal of Clinical Epidemiology, 84, pp. 27-29. DOI: 10.1016/j.jclinepi.2016.10.010 © 2017, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/en_UK
dc.titlePRECIS-2 helps researchers design more applicable RCTs while CONSORT Extension for Pragmatic Trials helps knowledge users decide whether to apply themen_UK
dc.typeJournal Articleen_UK
dc.rights.embargoreason[JCE Commentary 2016.pdf] : Publisher requires embargo of 12 months after formal publication.en_UK
dc.identifier.doi10.1016/j.jclinepi.2016.10.010en_UK
dc.identifier.pmid28137671en_UK
dc.citation.jtitleJournal of Clinical Epidemiologyen_UK
dc.citation.issn0895-4356en_UK
dc.citation.volume84en_UK
dc.citation.spage27en_UK
dc.citation.epage29en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedUnrefereeden_UK
dc.type.statusAM - Accepted Manuscripten_UK
dc.author.emailkirsty.loudon@stir.ac.uken_UK
dc.citation.date28/01/2017en_UK
dc.contributor.affiliationUniversity of Western Ontarioen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationNMAHPen_UK
dc.identifier.isi000402849500009en_UK
dc.identifier.scopusid2-s2.0-85013486013en_UK
dc.identifier.wtid536863en_UK
dc.contributor.orcid0000-0002-4449-6226en_UK
dc.date.accepted2016-10-08en_UK
dc.date.firstcompliantdepositdate2017-01-31en_UK
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