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dc.contributor.authorMonaghan, Seanen_UK
dc.contributor.authorThompson, Kim Den_UK
dc.contributor.authorSmith, Patricken_UK
dc.contributor.authorAdams, Alexandraen_UK
dc.contributor.editorAdams, Aen_UK
dc.description.abstractThe expanding aquaculture industry continues to encounter major challenges from highly contagious viruses. Control and eradication measures for lethal and economically damaging notifiable viral diseases involve ‘stamping out’ policies and surveillance strategies. Mass-culling of stock and restricted movement of fish and fish products, used to control the spread of notifiable diseases, has considerable impacts on the trade of fish products. Although effective, these measures are expensive and ethically complex and could possibly be reduced by emulating innovative vaccination strategies used by the terrestrial livestock industry. DIVA (differentiating infected from vaccinated animal) strategies provide a basis to vaccinate and contain disease outbreaks without compromising ‘disease-free’ status, as antibodies induced during infection can be used to distinguish from those induced by vaccination. The potential and feasibility of DIVA vaccination in aquaculture is explored here with reference to DIVA strategies applied in higher vertebrates. Three economically important notifiable viruses, causing major problems in three different cultured fish industries, are considered. The increased availability and application of sophisticated biotechnology tools has enabled improved prophylaxis and serological diagnosis for control of viral haemorrhagic septicaemia in rainbow trout, infectious salmon anaemia in Atlantic salmon and koi herpesvirus disease in carp. Improving the specificity of serological diagnostics in aquaculture in conjunction with suitable vaccines could enable the application of DIVA strategies, but the immunological variation between different fish species and contrasting pathobiological characteristics of different viruses determines the feasibility and potential of such DIVA approaches for aquaculture industries.en_UK
dc.publisherSpringer International Publishing AGen_UK
dc.relationMonaghan S, Thompson KD, Smith P & Adams A (2016) Potential of DIVA vaccines for Fish. In: Adams A (ed.) Fish Vaccines. Birkhauser Advances in Infectious Diseases. Basel, Switzerland: Springer International Publishing AG, pp. 143-173.;
dc.relation.ispartofseriesBirkhauser Advances in Infectious Diseasesen_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.subjectDIVA vaccineen_UK
dc.subjectfish diseaseen_UK
dc.subjectmarker vaccineen_UK
dc.subjectfish virusen_UK
dc.titlePotential of DIVA vaccines for Fishen_UK
dc.typePart of book or chapter of booken_UK
dc.rights.embargoreason[Monaghan et al 2016 - Potential of DIVA vaccines for fish.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.type.statusVoR - Version of Recorden_UK
dc.citation.btitleFish Vaccinesen_UK
dc.publisher.addressBasel, Switzerlanden_UK
dc.contributor.affiliationInstitute of Aquacultureen_UK
dc.contributor.affiliationThe Moredun Research Instituteen_UK
dc.contributor.affiliationInstitute of Aquacultureen_UK
dc.contributor.affiliationInstitute of Aquacultureen_UK
rioxxterms.typeBook chapteren_UK
local.rioxx.authorMonaghan, Sean|0000-0002-7692-7756en_UK
local.rioxx.authorThompson, Kim D|en_UK
local.rioxx.authorSmith, Patrick|en_UK
local.rioxx.authorAdams, Alexandra|en_UK
local.rioxx.projectInternal Project|University of Stirling|
local.rioxx.contributorAdams, A|en_UK
local.rioxx.filenameMonaghan et al 2016 - Potential of DIVA vaccines for fish.pdfen_UK
Appears in Collections:Aquaculture Book Chapters and Sections

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