Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/22731
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dc.contributor.authorRobertson, Tony-
dc.contributor.authorBatty, G David-
dc.contributor.authorDer, Geoff-
dc.contributor.authorGreen, Michael J-
dc.contributor.authorMcGlynn, Liane M-
dc.contributor.authorMcIntyre, Alan-
dc.contributor.authorShiels, Paul G-
dc.contributor.authorBenzeval, Michaela-
dc.date.accessioned2016-01-14T23:44:48Z-
dc.date.available2016-01-14T23:44:48Z-
dc.date.issued2012-07-23-
dc.identifier.othere41805-
dc.identifier.urihttp://hdl.handle.net/1893/22731-
dc.description.abstractLower socioeconomic status (SES) is strongly associated with an increased risk of morbidity and premature mortality, but it is not known if the same is true for telomere length, a marker often used to assess biological ageing. The West of Scotland Twenty-07 Study was used to investigate this and consists of three cohorts aged approximately 35 (N = 775), 55 (N = 866) and 75 years (N = 544) at the time of telomere length measurement. Four sets of measurements of SES were investigated: those collected contemporaneously with telomere length assessment, educational markers, SES in childhood and SES over the preceding twenty years. We found mixed evidence for an association between SES and telomere length. In 35-year-olds, many of the education and childhood SES measures were associated with telomere length, i.e. those in poorer circumstances had shorter telomeres, as was intergenerational social mobility, but not accumulated disadvantage. A crude estimate showed that, at the same chronological age, social renters, for example, were nine years (biologically) older than home owners. No consistent associations were apparent in those aged 55 or 75. There is evidence of an association between SES and telomere length, but only in younger adults and most strongly using education and childhood SES measures. These results may reflect that childhood is a sensitive period for telomere attrition. The cohort differences are possibly the result of survival bias suppressing the SES-telomere association; cohort effects with regard different experiences of SES; or telomere possibly being a less effective marker of biological ageing at older ages.en_UK
dc.language.isoen-
dc.publisherPublic Library of Science-
dc.relationRobertson T, Batty GD, Der G, Green MJ, McGlynn LM, McIntyre A, Shiels PG & Benzeval M (2012) Is telomere length socially patterned? Evidence from the West of Scotland Twenty-07 Study, PLoS ONE, 7 (7), Art. No.: e41805.-
dc.rights© 2012 Robertson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.-
dc.subjectAdolescenten_UK
dc.subjectAdulten_UK
dc.subjectAgeden_UK
dc.subjectCohort Studiesen_UK
dc.subjectEducational Statusen_UK
dc.subjectFemaleen_UK
dc.subjectHumansen_UK
dc.subjectMaleen_UK
dc.subjectMiddle Ageden_UK
dc.subjectScotlanden_UK
dc.subjectSocial Classen_UK
dc.subjectTelomereen_UK
dc.subjectTelomere Shorteningen_UK
dc.subjectTelomere: geneticsen_UK
dc.subjectTime Factorsen_UK
dc.subjectYoung Adulten_UK
dc.titleIs telomere length socially patterned? Evidence from the West of Scotland Twenty-07 Studyen_UK
dc.typeJournal Articleen_UK
dc.identifier.doihttp://dx.doi.org/10.1371/journal.pone.0041805-
dc.identifier.pmid22844525-
dc.citation.jtitlePLoS ONE-
dc.citation.issn1932-6203-
dc.citation.volume7-
dc.citation.issue7-
dc.citation.publicationstatusPublished-
dc.citation.peerreviewedRefereed-
dc.type.statusPublisher version (final published refereed version)-
dc.author.emailtony.robertson@stir.ac.uk-
dc.citation.date23/07/2012-
dc.contributor.affiliationHS - Management and Support-
dc.contributor.affiliationUniversity of Edinburgh-
dc.contributor.affiliationUniversity of Birmingham-
dc.contributor.affiliationUniversity of Glasgow-
dc.contributor.affiliationUniversity of Glasgow-
dc.contributor.affiliationUniversity of Glasgow-
dc.contributor.affiliationUniversity of Glasgow-
dc.contributor.affiliationUniversity of Glasgow-
dc.identifier.isi000306687700152-
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles

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