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dc.contributor.authorWiedemann, Agnesen_UK
dc.contributor.authorLim, Jensonen_UK
dc.contributor.authorCaron, Emmanuelleen_UK
dc.contributor.editorRosales, Cen_UK
dc.description.abstractPhagocytosis is a conserved cellular process in Eukaryotes. A multi-step process, it involves the recognition of paniculate material, e.g., microbes and apoptotic cells, their F-actin-driven engulfment and the subsequent destruction of the phagocytized material in phagolysosomes. Distinct sets of small GTP-binding proteins (Rap1, Arf6, Rho and Rab proteins) control and coordinate the successive steps of the phagocytic process. Moreover, these proteins are often targeted by microbial virulence factors. This review summarizes and discusses the evidence implicating Ras, Rho, Arf and Rab-family GTPases in the signalling pathways driving particle recognition and uptake.en_UK
dc.publisherLandes Bioscience/Springer Scienceen_UK
dc.relationWiedemann A, Lim J & Caron E (2005) Small GTP Binding Proteins and the Control of Phagocytic Uptake. In: Rosales C (ed.) Molecular Mechanisms of Phagocytosis. Medical Intelligence Unit. New York: Landes Bioscience/Springer Science, pp. 72-84.
dc.relation.ispartofseriesMedical Intelligence Uniten_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.titleSmall GTP Binding Proteins and the Control of Phagocytic Uptakeen_UK
dc.typePart of book or chapter of booken_UK
dc.rights.embargoreason[2004 Wiedermann et al review phagocytosis GTPases.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.type.statusVoR - Version of Recorden_UK
dc.citation.btitleMolecular Mechanisms of Phagocytosisen_UK
dc.publisher.addressNew Yorken_UK
dc.contributor.affiliationImperial College Londonen_UK
dc.contributor.affiliationBiological and Environmental Sciencesen_UK
dc.contributor.affiliationImperial College Londonen_UK
rioxxterms.typeBook chapteren_UK
local.rioxx.authorWiedemann, Agnes|en_UK
local.rioxx.authorLim, Jenson|0000-0001-7417-356Xen_UK
local.rioxx.authorCaron, Emmanuelle|en_UK
local.rioxx.projectInternal Project|University of Stirling|
local.rioxx.contributorRosales, C|en_UK
local.rioxx.filename2004 Wiedermann et al review phagocytosis GTPases.pdfen_UK
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