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dc.contributor.authorAnderson, Annie Sen_UK
dc.contributor.authorCraigie, Angelaen_UK
dc.contributor.authorCaswell, Stephenen_UK
dc.contributor.authorTreweek, Shaunen_UK
dc.contributor.authorStead, Martineen_UK
dc.contributor.authorMacleod, Maureenen_UK
dc.contributor.authorDaly, Fergusen_UK
dc.contributor.authorBelch, Jill J Fen_UK
dc.contributor.authorRodger, Jackieen_UK
dc.contributor.authorKirk, Alisonen_UK
dc.contributor.authorLudbrook, Anneen_UK
dc.contributor.authorRauchhaus, Petraen_UK
dc.contributor.authorNorwood, Patriciaen_UK
dc.contributor.authorThompson, Joyceen_UK
dc.contributor.authorWardle, Janeen_UK
dc.contributor.authorSteele, Roberten_UK
dc.description.abstractObjective: To evaluate the impact of a diet and physical activity intervention (BeWEL) on weight change in people with a body mass index >25 weight (kg)/height (m)2 at increased risk of colorectal cancer and other obesity related comorbidities. Design: Multicentre, parallel group, randomised controlled trial. Setting Four: Scottish National Health Service health boards. Participants 329 overweight or obese adults (aged 50 to 74 years) who had undergone colonoscopy after a positive faecal occult blood test result, as part of the national bowel screening programme, and had a diagnosis of adenoma confirmed by histopathology. 163 were randomised to intervention and 166 to control. Intervention: Participants were randomised to a control group (weight loss booklet only) or 12 month intervention group (three face to face visits with a lifestyle counsellor plus monthly 15 minute telephone calls). A goal of 7% reduction in body weight was set and participants received a personalised energy prescription (2508 kJ (600 kcal) below that required for weight maintenance) and bodyweight scales. Motivational interviewing techniques explored self assessed confidence, ambivalence, and personal values concerning weight. Behavioural strategies included goal setting, identifying intentions of implementation, self monitoring of body weight, and counsellor feedback about reported diet, physical activity, and weight change. Main outcome measures The primary outcome was weight change over 12 months. Secondary outcomes included changes in waist circumference, blood pressure, fasting cardiovascular biomarkers, and glucose metabolism variables, physical activity, diet, and alcohol consumption. Results At 12 months, data on the primary outcome were available for 148 (91%) participants in the intervention group and 157 (95%) in the control group. Mean weight loss was 3.50 kg (SD 4.91) (95% confidence interval 2.70 to 4.30) in the intervention group compared with 0.78 kg (SD 3.77) (0.19 to 1.38) in the control group. The group difference was 2.69 kg (95% confidence interval 1.70 to 3.67). Differences between groups were significant for waist circumference, body mass index, blood pressure, blood glucose level, diet, and physical activity. No reported adverse events were considered to be related to trial participation. Conclusions Significant weight loss can be achieved by a diet and physical activity intervention initiated within a national colorectal cancer screening programme, offering considerable potential for risk reduction of disease in older adults.en_UK
dc.publisherBMJ Publishing Groupen_UK
dc.relationAnderson AS, Craigie A, Caswell S, Treweek S, Stead M, Macleod M, Daly F, Belch JJF, Rodger J, Kirk A, Ludbrook A, Rauchhaus P, Norwood P, Thompson J, Wardle J & Steele R (2014) The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trial. BMJ, 348, Art. No.: g1823.
dc.rightsJournal is open-access. Open access publishing allows free access to and distribution of published articles where the author retains copyright of their work by employing a Creative Commons attribution licence. Proper attribution of authorship and correct citation details should be given.en_UK
dc.titleThe impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trialen_UK
dc.typeJournal Articleen_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.funderMedical Research Councilen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationInstitute for Social Marketingen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationNHS Taysideen_UK
dc.contributor.affiliationUniversity of Strathclydeen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationNHS Taysideen_UK
dc.contributor.affiliationUniversity College Londonen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.relation.funderprojectBeWEL the impact of body weight and physical activity intervention programme on adults at the risk of developing colorectal adenomasen_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
local.rioxx.authorAnderson, Annie S|en_UK
local.rioxx.authorCraigie, Angela|en_UK
local.rioxx.authorCaswell, Stephen|en_UK
local.rioxx.authorTreweek, Shaun|en_UK
local.rioxx.authorStead, Martine|0000-0002-3066-4604en_UK
local.rioxx.authorMacleod, Maureen|en_UK
local.rioxx.authorDaly, Fergus|en_UK
local.rioxx.authorBelch, Jill J F|en_UK
local.rioxx.authorRodger, Jackie|en_UK
local.rioxx.authorKirk, Alison|en_UK
local.rioxx.authorLudbrook, Anne|en_UK
local.rioxx.authorRauchhaus, Petra|en_UK
local.rioxx.authorNorwood, Patricia|en_UK
local.rioxx.authorThompson, Joyce|en_UK
local.rioxx.authorWardle, Jane|en_UK
local.rioxx.authorSteele, Robert|en_UK
local.rioxx.projectDUN001.028.R|Medical Research Council|
local.rioxx.filenamebmj 2014.pdfen_UK
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