Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/18989
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dc.contributor.authorMadan, Jason-
dc.contributor.authorChen, Yen-Fu-
dc.contributor.authorAveyard, Paul-
dc.contributor.authorWang, Dechao-
dc.contributor.authorYahaya, Ismail-
dc.contributor.authorMunafo, Marcus-
dc.contributor.authorBauld, Linda-
dc.contributor.authorWelton, Nicky-
dc.date.accessioned2015-10-05T23:12:33Z-
dc.date.issued2014-01-
dc.identifier.urihttp://hdl.handle.net/1893/18989-
dc.description.abstractHealth technology assessment requires the synthesis of evidence from multiple sources to assess the cost-effectiveness of competing interventions. However, the format of the available reported evidence is often complex. We present a case-study of electronic aids to smoking cessation, which raises various methodological challenges. The evidence base evaluated highly complex and diverse interventions, reporting one or both of two different, but related, outcome measures. Furthermore, there were differences between studies in the number and timing of follow-up times reported, whereas 12-month continuous abstinence is required in the cost-effectiveness analysis. We develop a categorization system to evaluate the interventions, and we use network meta-analysis of time-to-relapse model parameters to estimate coherent intervention effects for any pair of categories. We compare the fit of alternative time-to-relapse models and explore the effect of joint models for both outcome measures, which can be used to estimate treatment effects when a given outcome is not reported, so that all the available evidence can be combined.en_UK
dc.language.isoen-
dc.publisherWiley-Blackwell-
dc.relationMadan J, Chen Y, Aveyard P, Wang D, Yahaya I, Munafo M, Bauld L & Welton N (2014) Synthesis of evidence on heterogeneous interventions with multiple outcomes recorded over multiple follow-up times reported inconsistently: A smoking cessation case-study, Journal of the Royal Statistical Society – Series A, 177 (1), pp. 295-314.-
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.-
dc.subjectCost-effectivenessen_UK
dc.subjectEvidence synthesisen_UK
dc.subjectHealth technology assessmenten_UK
dc.subjectNetwork meta-analysisen_UK
dc.subjectSmoking cessationen_UK
dc.titleSynthesis of evidence on heterogeneous interventions with multiple outcomes recorded over multiple follow-up times reported inconsistently: A smoking cessation case-studyen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31T00:00:00Z-
dc.rights.embargoreasonThe publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.-
dc.identifier.doihttp://dx.doi.org/10.1111/rssa.12018-
dc.citation.jtitleJournal of the Royal Statistical Society – Series A-
dc.citation.issn0964-1998-
dc.citation.volume177-
dc.citation.issue1-
dc.citation.spage295-
dc.citation.epage314-
dc.citation.publicationstatusPublished-
dc.citation.peerreviewedRefereed-
dc.type.statusPublisher version (final published refereed version)-
dc.author.emaillinda.bauld@stir.ac.uk-
dc.citation.date09/08/2013-
dc.contributor.affiliationUniversity of Bristol-
dc.contributor.affiliationUniversity of Birmingham-
dc.contributor.affiliationUniversity of Birmingham-
dc.contributor.affiliationUniversity of Birmingham-
dc.contributor.affiliationUniversity of Birmingham-
dc.contributor.affiliationUniversity of Bristol-
dc.contributor.affiliationInstitute for Social Marketing-
dc.contributor.affiliationUniversity of Bristol-
dc.rights.embargoterms2999-12-31-
dc.rights.embargoliftdate2999-12-31-
dc.identifier.isi000329309600016-
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles

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