Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/18989
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dc.contributor.authorMadan, Jasonen_UK
dc.contributor.authorChen, Yen-Fuen_UK
dc.contributor.authorAveyard, Paulen_UK
dc.contributor.authorWang, Dechaoen_UK
dc.contributor.authorYahaya, Ismailen_UK
dc.contributor.authorMunafo, Marcusen_UK
dc.contributor.authorBauld, Lindaen_UK
dc.contributor.authorWelton, Nickyen_UK
dc.date.accessioned2015-10-05T23:12:33Z-
dc.date.available2015-10-05T23:12:33Zen_UK
dc.date.issued2014-01en_UK
dc.identifier.urihttp://hdl.handle.net/1893/18989-
dc.description.abstractHealth technology assessment requires the synthesis of evidence from multiple sources to assess the cost-effectiveness of competing interventions. However, the format of the available reported evidence is often complex. We present a case-study of electronic aids to smoking cessation, which raises various methodological challenges. The evidence base evaluated highly complex and diverse interventions, reporting one or both of two different, but related, outcome measures. Furthermore, there were differences between studies in the number and timing of follow-up times reported, whereas 12-month continuous abstinence is required in the cost-effectiveness analysis. We develop a categorization system to evaluate the interventions, and we use network meta-analysis of time-to-relapse model parameters to estimate coherent intervention effects for any pair of categories. We compare the fit of alternative time-to-relapse models and explore the effect of joint models for both outcome measures, which can be used to estimate treatment effects when a given outcome is not reported, so that all the available evidence can be combined.en_UK
dc.language.isoenen_UK
dc.publisherWiley-Blackwellen_UK
dc.relationMadan J, Chen Y, Aveyard P, Wang D, Yahaya I, Munafo M, Bauld L & Welton N (2014) Synthesis of evidence on heterogeneous interventions with multiple outcomes recorded over multiple follow-up times reported inconsistently: A smoking cessation case-study. Journal of the Royal Statistical Society – Series A, 177 (1), pp. 235-314. https://doi.org/10.1111/rssa.12018en_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.subjectCost-effectivenessen_UK
dc.subjectEvidence synthesisen_UK
dc.subjectHealth technology assessmenten_UK
dc.subjectNetwork meta-analysisen_UK
dc.subjectSmoking cessationen_UK
dc.titleSynthesis of evidence on heterogeneous interventions with multiple outcomes recorded over multiple follow-up times reported inconsistently: A smoking cessation case-studyen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-09en_UK
dc.rights.embargoreason[Madan et al_JRSS_2014.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.identifier.doi10.1111/rssa.12018en_UK
dc.citation.jtitleJournal of the Royal Statistical Society: Series Aen_UK
dc.citation.issn1467-985Xen_UK
dc.citation.issn0964-1998en_UK
dc.citation.volume177en_UK
dc.citation.issue1en_UK
dc.citation.spage235en_UK
dc.citation.epage314en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emaillinda.bauld@stir.ac.uken_UK
dc.citation.date09/08/2013en_UK
dc.contributor.affiliationUniversity of Bristolen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Bristolen_UK
dc.contributor.affiliationInstitute for Social Marketingen_UK
dc.contributor.affiliationUniversity of Bristolen_UK
dc.identifier.isiWOS:000329309600016en_UK
dc.identifier.scopusid2-s2.0-84881300703en_UK
dc.identifier.wtid680417en_UK
dc.date.filedepositdate2014-02-20en_UK
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles

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