Please use this identifier to cite or link to this item:
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles
Peer Review Status: Refereed
Title: Diamorphine for pain relief in labour: a randomised controlled trial comparing intramuscular injection and patient-controlled analgesia
Author(s): McInnes, Rhona
Hillan, Edith
Clark, Diana
Gilmour, Harper
Contact Email:
Keywords: Labor (Obstetrics)
Issue Date: Oct-2004
Date Deposited: 15-Apr-2013
Citation: McInnes R, Hillan E, Clark D & Gilmour H (2004) Diamorphine for pain relief in labour: a randomised controlled trial comparing intramuscular injection and patient-controlled analgesia. BJOG: An International Journal of Obstetrics and Gynaecology, 111 (10), pp. 1081-1089.
Abstract: Objectives: To compare the efficacy of diamorphine administered by a patient-controlled pump (patient-controlled analgesia) with intramuscular administration for pain relief in labour. Design: Randomised controlled trial. Setting: The South Glasgow University Hospitals NHS Trust. Sample: Primigravidae and multigravidae in labour at term (37-42 weeks). Methods: Women were randomised in labour to the study (patient-controlled analgesia) or control group (intramuscular). Randomisation was achieved through a random permuted block design stratified by parity. Study group women were given a loading dose of 1.2 mg diamorphine intravenously and then attached to the pump. Control group women received intramuscular diamorphine as per hospital protocol. Participants were also given 3 mg of buccal Stemetil. Data were collected throughout labour and at six postnatal weeks. Main outcome measures: Analgesia requirements during labour and women's satisfaction with the method of pain relief. Results: Women in the study group (patient-controlled analgesia) used significantly less diamorphine than women in the control group (intramuscular) but were significantly more likely to state that they were very dissatisfied with their use of diamorphine and were significantly more likely to opt out of the trial before the birth of the baby. The majority of women in both groups used other analgesia concurrent with diamorphine such as Entonox, aromatherapy or TENS. Conclusions: Patient-controlled analgesia administration of diamorphine for the relief of pain in labour offers no significant advantages over intramuscular administration. The results also suggest that diamorphine is a poor analgesic for labour pain irrespective of the mode of administration.
DOI Link: 10.1111/j.1471-0528.2004.00131.x
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Licence URL(s):

Files in This Item:
File Description SizeFormat 
Mcinnes et al 2004 - diamorphine.pdfFulltext - Published Version246.33 kBAdobe PDFUnder Embargo until 3000-01-01    Request a copy

Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependent on the depositor still being contactable at their original email address.

This item is protected by original copyright

Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

The metadata of the records in the Repository are available under the CC0 public domain dedication: No Rights Reserved

If you believe that any material held in STORRE infringes copyright, please contact providing details and we will remove the Work from public display in STORRE and investigate your claim.