Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/11036
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dc.contributor.authorCraigie, Angelaen_UK
dc.contributor.authorCaswell, Stephenen_UK
dc.contributor.authorPaterson, Caronen_UK
dc.contributor.authorTreweek, Shaunen_UK
dc.contributor.authorBelch, Jill J Fen_UK
dc.contributor.authorDaly, Fergusen_UK
dc.contributor.authorRodger, Jackieen_UK
dc.contributor.authorThompson, Joyceen_UK
dc.contributor.authorKirk, Alisonen_UK
dc.contributor.authorLudbrook, Anneen_UK
dc.contributor.authorStead, Martineen_UK
dc.contributor.authorWardle, Janeen_UK
dc.contributor.authorSteele, Roberten_UK
dc.contributor.authorAnderson, Annie Sen_UK
dc.date.accessioned2015-02-10T09:07:50Z-
dc.date.available2015-02-10T09:07:50Z-
dc.date.issued2011-03-25en_UK
dc.identifier.urihttp://hdl.handle.net/1893/11036-
dc.description.abstractBackground: Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second highest cause of cancer death in the UK. Most cases occur in people over 50 years and CRC often co-exists with other lifestyle related disorders including obesity, type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). These diseases share risk factors related to the metabolic syndrome including large body size, abnormal lipids and markers of insulin resistance indicating common aetiological pathways. Methods/Design: This 3 year study will be a two-arm, multicentre, randomised controlled trial comparing the BeWEL lifestyle (diet, physical activity and behaviour change) programme against usual care. The pre-trial development will take 6 months and participants will be recruited over a 12 month period and undertake the intervention and follow up for 12 months (total 24 months recruitment and intervention implementation) with a further 6 months for data collection, analysis and interpretation. Four hundred and fifty two participants who have had a colorectal adenoma detected and removed (through the national colorectal screening programme) will provide 80% power to detect a weight loss of 7% over 12 months. Primary outcomes are changes in body weight and waist circumference. Secondary outcomes will include cardiovascular risk factors, psycho-social measures and intervention costs. Discussion: The results from this study will enhance the evidence base for lifestyle change in patients at higher risk of chronic disease including obesity related cancers.en_UK
dc.language.isoenen_UK
dc.publisherBioMed Central Ltden_UK
dc.relationCraigie A, Caswell S, Paterson C, Treweek S, Belch JJF, Daly F, Rodger J, Thompson J, Kirk A, Ludbrook A, Stead M, Wardle J, Steele R & Anderson AS (2011) Study protocol for BeWEL: The impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas. BMC Public Health, 11 (184). https://doi.org/10.1186/1471-2458-11-184en_UK
dc.rights© 2011 Craigie et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_UK
dc.rights.urihttp://creativecommons.org/licenses/by/2.0/en_UK
dc.titleStudy protocol for BeWEL: The impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomasen_UK
dc.typeJournal Articleen_UK
dc.identifier.doi10.1186/1471-2458-11-184en_UK
dc.citation.jtitleBMC Public Healthen_UK
dc.citation.issn1471-2458en_UK
dc.citation.volume11en_UK
dc.citation.issue184en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.funderMedical Research Councilen_UK
dc.author.emailmartine.stead@stir.ac.uken_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationNHS Taysideen_UK
dc.contributor.affiliationNHS Taysideen_UK
dc.contributor.affiliationUniversity of Strathclydeen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationInstitute for Social Marketingen_UK
dc.contributor.affiliationUniversity College Londonen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.identifier.isiWOS:000289161300001en_UK
dc.identifier.scopusid2-s2.0-79953099485en_UK
dc.identifier.wtid733445en_UK
dc.contributor.orcid0000-0002-3066-4604en_UK
dc.date.filedepositdate2013-02-20en_UK
dc.relation.funderprojectBeWEL the impact of body weight and physical activity intervention programme on adults at the risk of developing colorectal adenomasen_UK
dc.relation.funderrefDUN001.028.Ren_UK
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles

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