Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/8779
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dc.contributor.authorBroad, Elizabeth Men_UK
dc.contributor.authorMaughan, Ronald Jen_UK
dc.contributor.authorGalloway, S Den_UK
dc.date.accessioned2018-02-15T02:11:39Z-
dc.date.available2018-02-15T02:11:39Z-
dc.date.issued2011-10en_UK
dc.identifier.urihttp://hdl.handle.net/1893/8779-
dc.description.abstractThe effects of 15 d of supplementation with L-carnitine L-tartrate (LC) on metabolic responses to graded-intensity exercise under conditions of altered substrate availability were examined. Fifteen endurance-trained male athletes undertook exercise trials after a 2-d high-carbohydrate diet (60% CHO, 25% fat) at baseline (D0), on Day 14 (D14), and after a single day of high fat intake (15% CHO, 70% fat) on Day 15 (D15) in a double-blind, placebo-controlled, pair-matched design. Treatment consisted of 3 g LC (2 g L-carnitine/d; n = 8) or placebo (P, n = 7) for 15 d. Exercise trials consisted of 80 min of continuous cycling comprising 20-min periods at each of 20%, 40%, 60%, and 80% VO2peak. There was no significant difference between whole-body rates of CHO and fat oxidation at any workload between D0 and D14 trials for either the P or LC group. Both groups displayed increased fat and reduced carbohydrate oxidation between the D14 and D15 trials (p less than .05). During the D15 trial, heart rate (p less than .05 for 20%, 40%, and 60% workloads) and blood glucose concentration (p less than .05 for 40% and 60% workloads) were lower during exercise in the LC group than in P. These responses suggest that LC may induce subtle changes in substrate handling in metabolically active tissues when fatty-acid availability is increased, but it does not affect whole-body substrate utilization during short-duration exercise at the intensities studied.en_UK
dc.language.isoenen_UK
dc.publisherHuman Kinetics Incen_UK
dc.relationBroad EM, Maughan RJ & Galloway SD (2011) Effects of exercise intensity and altered substrate availability on cardiovascular and metabolic responses to exercise after oral carnitine supplementation in athletes. International Journal of Sport Nutrition and Exercise Metabolism, 21 (5), pp. 385-397. http://journals.humankinetics.com/ijsnem-back-issues/ijsnem-volume-21-issue-5-october/effects-of-exercise-intensity-and-altered-substrate-availability-on-cardiovascular-and-metabolic-responses-to-exercise-after-oral-carnitine-supplementation-in-athletes; https://doi.org/10.1123/ijsnem.21.5.385en_UK
dc.rightsPublisher allows this work to be made available in this repository. Published in International Journal of Sport Nutrition and Exercise Metabolism by Human Kinetics with the following policy: The author retains the right to post an electronic version of the finalized article on electronic repositories controlled by the authors’ institution, provided that the electronic version is in PDF or other image capturing format.en_UK
dc.subjectL-carnitine L-tartrateen_UK
dc.subjectcyclistsen_UK
dc.subjectfat oxidationen_UK
dc.subjectcarbohydrate oxidationen_UK
dc.titleEffects of exercise intensity and altered substrate availability on cardiovascular and metabolic responses to exercise after oral carnitine supplementation in athletesen_UK
dc.typeJournal Articleen_UK
dc.identifier.doi10.1123/ijsnem.21.5.385en_UK
dc.citation.jtitleInternational Journal of Sport Nutrition and Exercise Metabolismen_UK
dc.citation.issn1526-484Xen_UK
dc.citation.volume21en_UK
dc.citation.issue5en_UK
dc.citation.spage385en_UK
dc.citation.epage397en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.identifier.urlhttp://journals.humankinetics.com/ijsnem-back-issues/ijsnem-volume-21-issue-5-october/effects-of-exercise-intensity-and-altered-substrate-availability-on-cardiovascular-and-metabolic-responses-to-exercise-after-oral-carnitine-supplementation-in-athletesen_UK
dc.author.emails.d.r.galloway@stir.ac.uken_UK
dc.contributor.affiliationAustralian Institute of Sporten_UK
dc.contributor.affiliationLoughborough Universityen_UK
dc.contributor.affiliationSporten_UK
dc.identifier.isiWOS:000296200100004en_UK
dc.identifier.scopusid2-s2.0-80053324636en_UK
dc.identifier.wtid783777en_UK
dc.contributor.orcid0000-0002-1622-3044en_UK
dcterms.dateAccepted2011-10-31en_UK
dc.date.filedepositdate2012-09-03en_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorBroad, Elizabeth M|en_UK
local.rioxx.authorMaughan, Ronald J|en_UK
local.rioxx.authorGalloway, S D|0000-0002-1622-3044en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2012-09-03en_UK
local.rioxx.licencehttp://www.rioxx.net/licenses/all-rights-reserved|2012-09-03|en_UK
local.rioxx.filename04_Broad IJSNEM_20100091.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source1526-484Xen_UK
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