http://hdl.handle.net/1893/8741
Appears in Collections: | Aquaculture Journal Articles |
Peer Review Status: | Refereed |
Title: | Proteomic analysis of rainbow trout (Oncorhynchus mykiss, Walbaum) serum after administration of probiotics in diets |
Author(s): | Brunt, Jason Hansen, Rasmus Jamieson, Derek Austin, Brian |
Contact Email: | brian.austin@stir.ac.uk |
Keywords: | Probiotic Fish disease Acute phase response Innate immunity Proteomics |
Issue Date: | 15-Feb-2008 |
Date Deposited: | 31-Aug-2012 |
Citation: | Brunt J, Hansen R, Jamieson D & Austin B (2008) Proteomic analysis of rainbow trout (Oncorhynchus mykiss, Walbaum) serum after administration of probiotics in diets. Veterinary Immunology and Immunopathology, 121 (3-4), pp. 199-205. https://doi.org/10.1016/j.vetimm.2007.09.010 |
Abstract: | The response of rainbowtrout (Oncorhynchusmykiss, Walbaum) towards probiotics present in the feed was investigated by examining the proteome of serum as a measure of the acute phase response (APR). Proteomicanalysis by two-dimensional electrophoresis (2D) concurrently with mass spectrometry was used to detect APR related proteins in rainbowtroutserum following feeding with probioticsAeromonas sobria GC2 and Bacillus sp. JB-1. Three candidate proteins increased following use of GC2, and were putatively identified as NADH dehydrogenase, dystrophin and mKIAA0350. Conversely, one of the proteins, which were induced following use of JB-1 was identified as transferrin. |
DOI Link: | 10.1016/j.vetimm.2007.09.010 |
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