Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/7726

Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Molecular cloning of troponin I expressed in fast white muscle of a teleost fish, the Atlantic herring (Clupea harengus L)
Authors: Hodgson, Paul
Leaver, Michael
George, Stephen
Maclean, David
Hastings, Kenneth E M
Contact Email: m.j.leaver@stir.ac.uk
Keywords: troponin I
muscle protein
fish
molecular sequence data
evolution
vertebrate
(Clupea harengus)
Issue Date: 2-May-1996
Publisher: Elsevier
Citation: Hodgson P, Leaver M, George S, Maclean D & Hastings KEM (1996) Molecular cloning of troponin I expressed in fast white muscle of a teleost fish, the Atlantic herring (Clupea harengus L), Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1306 (2-3), pp. 142-146.
Abstract: By cDNA cloning and 5′-RACE analysis we characterised a Clupea harengus troponin I mRNA expressed in larvae and in adult white (fast) muscle, but not in red (slow) or cardiac muscle. The mRNA encodes a TnI protein of the short chain length (176 residues) N-terminally truncated type previously observed only in tetrapod skeletal muscles. Despite its expression specificity the herring TnI does not particularly resemble the tetrapod fast skeletal muscle isoform in sequence but appears to be outside of the tetrapod TnIfast/TnIslow/TnIcardiac isoform family. Surprisingly, the actin/TnC-binding sequence resembles that of arthropod, rather than tetrapod vertebrate, troponin I's and has, besides, unique features not seen in any other troponin I's, vertebrate or invertebrate.
Type: Journal Article
URI: http://hdl.handle.net/1893/7726
URL: http://www.sciencedirect.com/science/article/pii/0167478196000334
DOI Link: http://dx.doi.org/10.1016/0167-4781(96)00033-4
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: University of Stirling
Aquaculture
Aquaculture
Northern Ontario School of Medicine
McGill University

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