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Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Induction of piscine metallothionein as a primary response to heavy metal pollutants: applicability of new sensitive molecular probes
Authors: Kille, Peter
Kay, John
Leaver, Michael
George, Stephen
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Keywords: Fish metallothioneins
Amino acid sequences
Cuitured cells
Heavy metals
Issue Date: Jun-1992
Publisher: Elsevier
Citation: Kille P, Kay J, Leaver M & George S (1992) Induction of piscine metallothionein as a primary response to heavy metal pollutants: applicability of new sensitive molecular probes, Aquatic Toxicology, 22 (4), pp. 279-286.
Abstract: Induction of metallothionein (MT) in piscine tissues is a primary response to heavy metals which is now being utilised for environmental monitoring. Recent molecular biological and immunological studies have revealed a strong structural conservation amongst fish MTs and clear differences from their mammalian and avian orthologues. Probes derived from these studies are now being utilised to investigate the functional role of MT in metal regulation and cytotoxicity.
Type: Journal Article
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Affiliation: Cardiff University
University of Wales College of Cardiff

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