Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/7603
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Identification of cytochrome P4501B-like sequences in two teleost fish species (scup, Stenotomus chrysops and plaice, Pleuronectes platessa) and in a cetacean (striped dolphin, Stenella coeruleoalba)
Authors: Godard, Celine A J
Leaver, Michael
Said, Maya R
Dickerson, Richard L
George, Stephen
Stegeman, John J
Contact Email: m.j.leaver@stir.ac.uk
Keywords: cytochrome P450
gene sequence
dolphin
cloning
scup
Issue Date: Jul-2000
Publisher: Elsevier
Citation: Godard CAJ, Leaver M, Said MR, Dickerson RL, George S & Stegeman JJ (2000) Identification of cytochrome P4501B-like sequences in two teleost fish species (scup, Stenotomus chrysops and plaice, Pleuronectes platessa) and in a cetacean (striped dolphin, Stenella coeruleoalba), Marine Environmental Research, 50 (1- 5), pp. 7-10.
Abstract: The cytochromes P450 (CYP) constitute a multigene family of enzymes playing a critical role in the oxidation of many endogenous and xenobiotic substrates. The CYP1 family is of particular interest in environmental toxicology because its members are dominant in the metabolism of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs) and aryl amines. Three members of the CYP1 family, CYP1A1, CYP1A2, and CYP1B1, have been identified in mammals. We report here on the identification and cloning of cytochrome P4501B-like sequences from two teleost fish species and a marine mammal. Sequences clustering with CYP1B1 in phylogenetic analysis were obtained from liver cDNA of scup (Stenotomus chrysops), genomic DNA of plaice (Pleuronectes platessa), and liver cDNA of striped dolphin (Stenella coeruleoalba).
Type: Journal Article
URI: http://hdl.handle.net/1893/7603
URL: http://www.sciencedirect.com/science/article/pii/S0141113600000520
DOI Link: http://dx.doi.org/10.1016/S0141-1136(00)00052-0
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: Woods Hole Oceanographic Institution
Aquaculture
Woods Hole Oceanographic Institution
Texas Tech University
Aquaculture
Woods Hole Oceanographic Institution

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