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Appears in Collections:Faculty of Health Sciences and Sport Journal Articles
Peer Review Status: Refereed
Title: Independent and combined effects of amino acids and glucose after resistance exercise
Authors: Miller, Sharon L
Tipton, Kevin
Chinkes, David L
Wolf, Steven E
Wolfe, Robert R
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Keywords: stable
urea production
leg balance
human subjects
Issue Date: Mar-2003
Publisher: American College of Sports Medicine
Citation: Miller SL, Tipton K, Chinkes DL, Wolf SE & Wolfe RR (2003) Independent and combined effects of amino acids and glucose after resistance exercise, Medicine and Science in Sports and Exercise, 35 (3), pp. 449-455.
Abstract: PURPOSE: This study was designed to assess the independent and combined effects of a dose of amino acids (approximately 6 g) and/or carbohydrate (approximately 35 g) consumed at 1 and 2 h after resistance exercise on muscle protein metabolism. METHODS: Following initiation of a primed constant infusion of H -phenylalanine and N-urea, volunteers performed leg resistance exercise and then ingested one of three drinks (amino acids (AA), carbohydrate (CHO), or AA and CHO (MIX)) at 1- and 2-h postexercise.(5) RESULTS: Total net uptake of phenylalanine across the leg over 3 h was greatest in response to MIX and least in CHO. The individual values for CHO, MIX, and AA were 53 +/- 6, 114 +/- 38, and 71 +/- 13 mg x leg x 3h. Stimulation of net uptake in MIX was due to increased muscle protein synthesis. CONCLUSIONS: These findings indicate that the combined effect on net muscle protein synthesis of carbohydrate and amino acids given together after resistance exercise is roughly equivalent to the sum of the independent effects of either given alone. The individual effects of carbohydrate and amino acids are likely dependent on the amount of each that is ingested. Further, prior intake of amino acids and carbohydrate does not diminish the metabolic response to a second comparable dose ingested 1h later.
Type: Journal Article
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Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: University of Texas Medical Branch
University of Texas
University of Texas Medical Branch
University of Arkansas for Medical Sciences

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