Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/7304
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Bacillus subtilis AB1 controls Aeromonas infection in rainbow trout (Oncorhynchus mykiss, Walbaum)
Authors: Newaj-Fyzul, Aweeda
Adesiyun, Abiodun A
Mutani, A
Ramsubhag, A
Brunt, Jason
Austin, Brian
Contact Email: brian.austin@stir.ac.uk
Keywords: Aeromonas
Bacillus subtilis AB1
Fish disease
Innate immunity
Probiotic
Specific immunity
Issue Date: Nov-2007
Publisher: Wiley-Blackwell
Citation: Newaj-Fyzul A, Adesiyun AA, Mutani A, Ramsubhag A, Brunt J & Austin B (2007) Bacillus subtilis AB1 controls Aeromonas infection in rainbow trout (Oncorhynchus mykiss, Walbaum), Journal of Applied Microbiology, 103 (5), pp. 1699-1706.
Abstract: Aim: To develop a probiotic with effectiveness against Aeromonas sp., which was pathogenic to rainbow trout. Methods and Results: When Bacillus subtilis AB1, which was obtained from fish intestine, was administered for 14 days to rainbow trout in feed at a concentration of 107 cells per gram either as viable, formalized or sonicated cells or as cell-free supernatant, the fish survived challenge with the pathogen. AB1 stimulated immune parameters, specifically stimulating respiratory burst, serum and gut lysozyme, peroxidase, phagocytic killing, total and a1-antiprotease and lymphocyte populations. Conclusions: Bacillus subtilis AB1 was effective as a probiotic at controlling infections by a fish-pathogenic Aeromonas sp. in rainbow trout. Significance and Impact of the Study: Disease control in fish is possible by means of the oral application of live and inactivated cells and their subcellular components with the mode of action reflecting stimulation of the innate immune response.
Type: Journal Article
URI: http://hdl.handle.net/1893/7304
DOI Link: http://dx.doi.org/10.1111/j.1365-2672.2007.03402.x
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: Heriot-Watt University
University of the West Indies
University of the West Indies
University of the West Indies
Heriot-Watt University
Aquaculture

Files in This Item:
File Description SizeFormat 
Austin_2007_Bacillus_subtilis_AB1.pdf147.21 kBAdobe PDFUnder Embargo until 31/12/2999     Request a copy

Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependant on the depositor still being contactable at their original email address.

This item is protected by original copyright



Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.