Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/7195
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dc.contributor.authorBassett, D I-
dc.date.accessioned2015-05-28T23:31:26Z-
dc.date.issued2003-07-
dc.identifier.urihttp://hdl.handle.net/1893/7195-
dc.description.abstractThe cytokine Macrophage Stimulating 1 (MST1/MSP/Hepatocyte Growth Factor-Like) is a ligand of the Met-related MST1-Receptor (MST1R/RON). Although MST1-deficient mice are viable, MST1R is essential in mice before gastrulation for implantation, and is a known oncogene in man. Here I report the identification, sequence, chromosomal location and embryonic expression of a novel zebrafish orthologue, termed macrophage stimulating 1 (mst1). mst1 shows a striking restriction of expression to the dorsal side of the embryo prior to gastrulation, and as gastrulation and somitogenesis proceed is expressed sequentially in the presumptive neurectoderm, the notochord, the somites, endodermal cells and in the syncytial yolk. This dynamic pattern is largely conserved in tetrapod vertebrates, suggesting that the appearance of MST1, may have played an early role in the evolution of the vertebrate body plan.en_UK
dc.language.isoen-
dc.publisherSpringer Link-
dc.relationBassett DI (2003) Identification and developmental expression of a macrophage stimulating 1/hepatocyte growth factor-like 1 orthologue in the zebrafish, Development Genes and Evolution, 213 (7), pp. 360-362.-
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.-
dc.subjectMST1 (macrophage stimulating 1)en_UK
dc.subjectHGFL (Hepatocyte growth factor-like)en_UK
dc.subjectZebrafishen_UK
dc.subjectNeurogenesisen_UK
dc.subjectSomitesen_UK
dc.titleIdentification and developmental expression of a macrophage stimulating 1/hepatocyte growth factor-like 1 orthologue in the zebrafishen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31T00:00:00Z-
dc.rights.embargoreasonThe publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.-
dc.identifier.doihttp://dx.doi.org/10.1007/s00427-003-0339-3-
dc.citation.jtitleDevelopment Genes and Evolution-
dc.citation.issn0949-944X-
dc.citation.volume213-
dc.citation.issue7-
dc.citation.spage360-
dc.citation.epage362-
dc.citation.publicationstatusPublished-
dc.citation.peerreviewedRefereed-
dc.type.statusPublisher version (final published refereed version)-
dc.author.emaild.i.bassett@stir.ac.uk-
dc.citation.date23/05/2003-
dc.contributor.affiliationAquaculture (Machrihanish)-
dc.rights.embargoterms2999-12-31-
dc.rights.embargoliftdate2999-12-31-
dc.identifier.isi000184686500006-
Appears in Collections:Aquaculture Journal Articles

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