Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/7192

Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Recode-2: new design, new search tools, and many more genes
Authors: Bekaert, Michaël
Firth, Andrew E
Zhang, Yan
Gladyshev, Vadim N
Atkins, John F
Baranov, Pavel V
Contact Email: michael.bekaert@stir.ac.uk
Issue Date: Jan-2010
Publisher: Oxford University Press
Citation: Bekaert M, Firth AE, Zhang Y, Gladyshev VN, Atkins JF & Baranov PV (2010) Recode-2: new design, new search tools, and many more genes, Nucleic Acids Research, 38 (Supplement 1), pp. D69-D74.
Abstract: 'Recoding' is a term used to describe non-standard read-out of the genetic code, and encompasses such phenomena as programmed ribosomal frameshifting, stop codon readthrough, selenocysteine insertion and translational bypassing. Although only a small proportion of genes utilize recoding in protein synthesis, accurate annotation of ‘recoded’ genes lags far behind annotation of 'standard' genes. In order to address this issue, provide a service to researchers in the field, and offer training data for developers of gene-annotation software, we have gathered together known cases of recoding within the Recode database. Recode-2 is an improved and updated version of the database. It provides access to detailed information on genes known to utilize translational recoding and allows complex search queries, browsing of recoding data and enhanced visualization of annotated sequence elements. At present, the Recode-2 database stores information on approximately 1500 genes that are known to utilize recoding in their expression—a factor of approximately three increase over the previous version of the database. Recode-2 is available at http://recode.ucc.ie
Type: Journal Article
URI: http://hdl.handle.net/1893/7192
DOI Link: http://dx.doi.org/10.1093/nar/gkp788
Rights: Publisher policy allows this work to be made available in this repository. Published in Nucleic Acids Research by Oxford University Press. Nucleic Acids Research (2010) 38 (suppl 1): D69-D74. http://nar.oxfordjournals.org/content/38/suppl_1/D69
Affiliation: Aquaculture
University College Cork
Harvard Medical School
Harvard Medical School
University of Utah
University College Cork

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