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Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: The zebrafish as a model for muscular dystrophy and congenital myopathy
Authors: Bassett, D I
Currie, Peter D
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Issue Date: 15-Oct-2003
Publisher: Oxford University Press
Citation: Bassett DI & Currie PD (2003) The zebrafish as a model for muscular dystrophy and congenital myopathy, Human Molecular Genetics, 12 (Supplement 2), pp. R265-R270.
Abstract: The muscular dystrophies and congenital myopathies are inherited diseases of the skeletal muscle, which lead to a loss of muscle function and are often fatal. While many of the loci involved are already known, these conditions remain incurable, and genetic models are being developed in an effort to understand the pathological mechanisms involved. Recently several papers have shown that the zebrafish, which is now widely used in developmental genetic studies, will provide a useful addition to our toolkit in this regard. Here we describe these studies, including a zebrafish model of what is potentially the novel pathological mechanism of muscle attachment failure in Duchenne and other muscular dystrophies.
Type: Journal Article
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Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Notes: Review article.
Affiliation: Aquaculture (Machrihanish)
Victor Chang Cardiac Research Institute

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