Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/3581

Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Transcriptomic analyses of intestinal gene expression of juvenile Atlantic cod (Gadus morhua) fed diets with Camelina oil as replacement for fish oil
Authors: Morais, Sofia
Edvardsen, Rolf B
Tocher, Douglas R
Bell, J Gordon
Contact Email: drt1@stir.ac.uk
Keywords: Aquaculture
Atlantic cod
Intestine
Transcriptome
Microarray
gene expression
Alternative feeds
Camelina oil
Fish oil
Replacement
Issue Date: Mar-2012
Publisher: Elsevier
Citation: Morais S, Edvardsen RB, Tocher DR & Bell JG (2012) Transcriptomic analyses of intestinal gene expression of juvenile Atlantic cod (Gadus morhua) fed diets with Camelina oil as replacement for fish oil, Comparative Biochemistry and Physiology - Part B: Biochemistry and Molecular Biology, 161 (3), pp. 283-293.
Abstract: For aquaculture of marine species to continue to expand, dietary fish oil (FO) must be replaced with more sustainable vegetable oil (VO) alternatives. Most VO are rich in n-6 polyunsaturated fatty acids (PUFA) and few are rich in n-3 PUFA but Camelina oil (CO) is unique in that, besides high 18:3n-3 and n-3/n-6 PUFA ratio, it also contains substantial long-chain monoenes, commonly found in FO. Cod (initial weight ~1.4 g) were fed for 12 weeks diets in which FO was replaced with CO. Growth performance, feed efficiency and biometric indices were not affected but lipid levels in liver and intestine tended to increase and those of flesh, decrease, with increasing dietary CO although only significantly for intestine. Reflecting diet, tissue n-3 long-chain PUFA levels decreased whereas 18:3n-3 and 18:2n-6 increased with inclusion of dietary CO. Dietary replacement of FO by CO did not induce major metabolic changes in intestine, but affected genes with potential to alter cellular proliferation and death as well as change structural properties of intestinal muscle. Although the biological effects of these changes are unclear, given the important role of intestine in nutrient absorption and health, further attention should be given to this organ in future.
Type: Journal Article
URI: http://hdl.handle.net/1893/3581
DOI Link: http://dx.doi.org/10.1016/j.cbpb.2011.12.004
Rights: Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology by Elsevier.; This is the peer reviewed version of this article.; NOTICE: this is the author’s version of a work that was accepted for publication in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, VOL 161, ISSUE 3, (March 2012), DOI: 10.1016/j.cbpb.2011.12.004.
Affiliation: Aquaculture
Institute of Marine Research, Norway
Aquaculture
Aquaculture

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