STORRE
STORRE: Stirling Online Research Repository
http://hdl.handle.net/1893/34151| Appears in Collections: | Faculty of Health Sciences and Sport Journal Articles |
| Peer Review Status: | Refereed |
| Title: | Safety and efficacy of e-cigarettes versus nicotine patches when used to help pregnant smokers quit. A randomised controlled trial |
| Author(s): | Hajek, Peter Przulj, Dunja Pesola, Francesca Griffiths, Christopher Walton, Robert McRobbie, Hayden Coleman, Tim Lewis, Sarah Whitemore, Rachel Clark, Miranda Ussher, Michael Sinclair, Lesley Seager, Emilie Cooper, Sue Bauld, Linda Naughton, Felix Saseni, Peter Manyonda, Isaac Myers Smith, Katie |
| Contact Email: | aileen.paton@stir.ac.uk |
| Date Deposited: | 11-Apr-2022 |
| Citation: | Hajek P, Przulj D, Pesola F, Griffiths C, Walton R, McRobbie H, Coleman T, Lewis S, Whitemore R, Clark M, Ussher M, Sinclair L, Seager E, Cooper S, Bauld L, Naughton F, Saseni P, Manyonda I & Myers Smith K (2022) Safety and efficacy of e-cigarettes versus nicotine patches when used to help pregnant smokers quit. A randomised controlled trial. Nature Medicine. |
| Abstract: | Nicotine replacement therapy is commonly offered to pregnant women who smoke to help them quit, but it has limited efficacy in this group. E-cigarettes are also used by pregnant smokers, but their safety and efficacy in pregnancy are unknown. Here we report the results of comparing nicotine patches with refillable e-cigarettes in a randomised controlled trial involving 1,140 participants. In the unadjusted primary analysis, validated prolonged quit rates at the end of pregnancy in the two study arms were not significantly different, but some abstainers in the patch arm used e-cigarettes. In a pre-specified sensitivity analysis excluding abstainers using non-allocated products, e-cigarettes were markedly more effective than patches.Low birthweight ( |
| Rights: | This item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. |
| Notes: | Output Status: Forthcoming |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Hajek_2022-Nature Medicine (1).pdf | Fulltext - Accepted Version | 1.1 MB | Adobe PDF | Under Embargo until 2024-09-30 Request a copy |
Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependent on the depositor still being contactable at their original email address.
This item is protected by original copyright |
Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
The metadata of the records in the Repository are available under the CC0 public domain dedication: No Rights Reserved https://creativecommons.org/publicdomain/zero/1.0/
If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.