|Appears in Collections:||School of Sport Journal Articles|
|Peer Review Status:||Refereed|
|Title:||Postexercise Muscle Glycogen Synthesis with Combined Glucose and Fructose Ingestion|
|Authors:||Wallis, Gareth A|
Hulston, Carl J
Mann, Christopher H
Roper, Helen P
Jeukendrup, Asker E
|Publisher:||Lippincott Williams and Wilkins / American College of Sports Medicine|
|Citation:||Wallis GA, Hulston CJ, Mann CH, Roper HP, Tipton K & Jeukendrup AE (2008) Postexercise Muscle Glycogen Synthesis with Combined Glucose and Fructose Ingestion, Medicine and Science in Sports and Exercise, 40 (10), pp. 1789-1794.|
|Abstract:||Purpose: To evaluate the efficacy of using combined glucose and fructose (GF) ingestion as a means to stimulate short-term (4 h) postexercise muscle glycogen synthesis compared to glucose only (G). Methods: On two separate occasions, six endurance-trained men performed an exhaustive glycogen-depleting exercise bout followed by a 4-h recovery period. Muscle biopsy samples were obtained from the vastus lateralis muscle at 0, 1, and 4 h after exercise. Subjects ingested carbohydrate solutions containing G (90 gIhj1) or GF (G = 60 gIhj1; F = 30 gIhj1) commencing immediately after exercise and every 30 min thereafter. Results: Immediate postexercise muscle glycogen concentrations were similar in both trials (G = 128 T 25 mmolIkgj1 dry muscle (dm) vs GF = 112 T 16 mmolIkgj1 dm; P 9 0.05). Total glycogen storage during the 4-h recovery period was 176 T 33 and 155 T 31 mmolIkgj1 dm for G and GF, respectively (G vs GF, P 9 0.05). Hence, mean muscle glycogen synthesis rates during the 4-h recovery period did not differ between the two conditions (G = 44 T 8 mmolIkgj1 dmIhj1 vs GF = 39 T 8 mmolIkgj1 dmIhj1, P 9 0.05). Plasma glucose and serum insulin responses during the recovery period were similar in both conditions, although plasma lactate concentrations were significantly elevated during GF compared to G (by È0.8 mmolILj1, P G 0.05). Conclusions: Glucose and glucose/fructose (2:1 ratio) solutions, ingested at a rate of 90 gIhj1, are equally effective at restoring muscle glycogen in exercised muscles during the recovery from exhaustive exercise|
|Rights:||Copyright 2008 by the American College of Sports Medicine.; The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author; you can only request a copy if you wish to use this work for your own research or private study.|
|Affiliation:||University of Birmingham|
University of Birmingham
Birmingham Women’s Hospit
Birmingham Heartlands Hospital
Sport - Academic
University of Birmingham
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