Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/26228
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dc.contributor.authorMacLean, Catrionaen_UK
dc.contributor.authorDillon, John Fen_UK
dc.contributor.authorBabraj, John Aen_UK
dc.contributor.authorVollaard, Nielsen_UK
dc.date.accessioned2018-05-12T13:44:10Z-
dc.date.available2018-05-12T13:44:10Z-
dc.date.issued2018en_UK
dc.identifier.urihttp://hdl.handle.net/1893/26228-
dc.description.abstractObjectives: Exercise is an important part of disease management in patients with non-alcoholic fatty liver disease (NAFLD), but adherence to current exercise recommendations is poor. Novel low-volume sprint interval training (SIT) protocols with total training time commitments of ≤30 min per week have been shown to improve cardiometabolic risk and functional capacity in healthy sedentary participants, but the efficacy of such protocols in the management of NAFLD remains unknown. The aim of the present study was to examine whether a low-volume SIT protocol can be used to improve liver function, insulin resistance, body composition, physical fitness, cognitive function and general well-being in patients with NAFLD.  Methods: In the present study, 7 men and 2 women with NAFLD (age: 45±8 y, BMI: 28.7±4.1 kg·m−2) completed a 6-week control period followed by 6 weeks of twice-weekly SIT sessions (5-10×6-s ‘all-out’ cycle sprints). Body composition, blood pressure, liver function, metabolic function, functional capacity, cognitive function and quality of life were assessed at baseline, following the control period, and following the SIT intervention.  Results: Walking speed during the walk test (+12%), estimated V̇O2max (+8%), verbal fluency (+44%), and blood platelet count (+12%; all p<0.05) significantly increased during the control period. These measures remained significantly raised compared to baseline following the SIT intervention, but did not significantly change any further compared to the post-control time-point. Diastolic blood pressure decreased from 87±10 to 77±8 mm Hg from the end of the control period to the end of the SIT intervention (p<0.05).  Conclusion: This study does not support the use of 6 weeks of a low volume SIT protocol involving twice-weekly sessions with 5-10×6-s ‘all-out’ cycle sprints as an intervention for NAFLD disease management.en_UK
dc.language.isoenen_UK
dc.publisherTaylor and Francisen_UK
dc.relationMacLean C, Dillon JF, Babraj JA & Vollaard N (2018) The effect of low volume sprint interval training in patients with non-alcoholic fatty liver disease. Physician and Sportsmedicine, 46 (1), pp. 87-92. https://doi.org/10.1080/00913847.2018.1411171en_UK
dc.rightsThis item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. This is an Accepted Manuscript of an article published by Taylor & Francis Group in The Physician and Sportsmedicine on 29 Nov 2017, available online: http://www.tandfonline.com/10.1080/00913847.2018.1411171en_UK
dc.subjectSITen_UK
dc.subjectall-outen_UK
dc.subjectNAFLDen_UK
dc.subjectNASHen_UK
dc.subjectliver functionen_UK
dc.subjectphysical functionen_UK
dc.titleThe effect of low volume sprint interval training in patients with non-alcoholic fatty liver diseaseen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2018-11-30en_UK
dc.rights.embargoreason[MacLean et al 2017 PSM revised.pdf] Publisher requires embargo of 12 months after formal publication.en_UK
dc.identifier.doi10.1080/00913847.2018.1411171en_UK
dc.identifier.pmid29183220en_UK
dc.citation.jtitlePhysician and Sportsmedicineen_UK
dc.citation.issn0091-3847en_UK
dc.citation.volume46en_UK
dc.citation.issue1en_UK
dc.citation.spage87en_UK
dc.citation.epage92en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusAM - Accepted Manuscripten_UK
dc.author.emailn.vollaard@stir.ac.uken_UK
dc.citation.date29/11/2017en_UK
dc.contributor.affiliationUniversity of Bathen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Abertayen_UK
dc.contributor.affiliationSporten_UK
dc.identifier.isiWOS:000423678500015en_UK
dc.identifier.scopusid2-s2.0-85035747277en_UK
dc.identifier.wtid882763en_UK
dc.contributor.orcid0000-0002-4576-8879en_UK
dc.date.accepted2017-11-27en_UK
dcterms.dateAccepted2017-11-27en_UK
dc.date.filedepositdate2017-11-29en_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionAMen_UK
local.rioxx.authorMacLean, Catriona|en_UK
local.rioxx.authorDillon, John F|en_UK
local.rioxx.authorBabraj, John A|en_UK
local.rioxx.authorVollaard, Niels|0000-0002-4576-8879en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2018-11-30en_UK
local.rioxx.licencehttp://www.rioxx.net/licenses/under-embargo-all-rights-reserved||2018-11-29en_UK
local.rioxx.licencehttp://www.rioxx.net/licenses/all-rights-reserved|2018-11-30|en_UK
local.rioxx.filenameMacLean et al 2017 PSM revised.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source0091-3847en_UK
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