Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/25257
Appears in Collections:Faculty of Social Sciences Journal Articles
Peer Review Status: Refereed
Title: Estimating the burden of early onset dementia; systematic review of disease prevalence
Authors: Lambert, Matt A
Bickel, Horst
Prince, Martin
Fratiglioni, Laura
Von, Strauss Eva
Frydecka, Dorota
Kiejna, Andrzej
Georges, Jean
Reynish, Emma
Contact Email: emma.reynish@stir.ac.uk
Keywords: Alzheimer's dementia
early onset dementia
pre-senile dementia
prevalence
Issue Date: Apr-2014
Citation: Lambert MA, Bickel H, Prince M, Fratiglioni L, Von Strauss E, Frydecka D, Kiejna A, Georges J & Reynish E (2014) Estimating the burden of early onset dementia; systematic review of disease prevalence, European Journal of Neurology, 21 (4), pp. 563-569.
Abstract: Dementia is more common in older age but a number of people develop symptoms at a younger age and are said to have early onset dementia (EOD). Those with EOD face different challenges to those with onset later in life. It has been difficult to quantify this disease burden. This is a systematic review of papers reporting on the prevalence of EOD. A search of Medline and Embase was performed. This was followed by a hand search of the references of these papers. Eleven suitable studies were included. All of the data was from more economically developed countries. The studies were heterogeneous in their design hindering direct comparison. The majority of the papers looked at all types of dementia although many gave a breakdown of the prevalence of different subgroups. A variety of diagnostic criteria was employed. Figures of 38 to 260 per 100 000 are quoted by papers looking at various different types of dementia together with an onset of between 30 and 64 or up to 420 per 100 000 for those aged 55-64. Prevalence rises as age approaches 65. Epidemiological data for prevalence rates for EOD are sparse. EOD remains a rare condition with low case numbers. Assimilation and comparison of results from existing studies is difficult due to methodological heterogeneity. Cross-national standardization of methodology should be a priority for future research in this area. © 2014 EFNS.
DOI Link: http://dx.doi.org/10.1111/ene.12325
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.

Files in This Item:
File Description SizeFormat 
Lambert_et_al-2014-European_Journal_of_Neurology.pdf2.15 MBAdobe PDFUnder Embargo until 31/12/2999     Request a copy

Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependent on the depositor still being contactable at their original email address.



This item is protected by original copyright



Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.