|Appears in Collections:||Computing Science and Mathematics Conference Papers and Proceedings|
|Peer Review Status:||Refereed|
|Authors:||Godley, Paul Michael|
|Title:||Optimisation of cancer chemotherapy schedules using directed intervention crossover approaches|
|Citation:||Godley PM, Cowie J, Cairns D, McCall J & Howie C (2008) Optimisation of cancer chemotherapy schedules using directed intervention crossover approaches IEEE Congress on Evolutionary Computation, 2008. CEC 2008. (IEEE World Congress on Computational Intelligence), IEEE Congress on Evolutionary Computation 2008, CEC 2008, Piscataway, NJ: IEEE (Institute of Electrical and Electronics Engineers), pp. 2532-2537.|
|Series/Report no.:||IEEE World Congress on Computational Intelligence|
|Conference Name:||IEEE Congress on Evolutionary Computation 2008, CEC 2008|
|Abstract:||This paper describes two directed intervention crossover approaches that are applied to the problem of deriving optimal cancer chemotherapy treatment schedules. Unlike traditional uniform crossover (UC), both the calculated expanding bin (CalEB) method and targeted intervention with stochastic selection (TInSSel) approaches actively choose an intervention level and spread based on the ﬁtness of the parents selected for crossover. Our results indicate that these approaches lead to signiﬁcant improvements over UC when applied to cancer chemotherapy scheduling.|
|Rights:||Copyright IEEE; ©2008 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE. http://www.ieee.org/publications_standards/publications/rights/rights_policies.html; The publisher has not responded to our queries therefore this work cannot be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author; you can only request a copy if you wish to use this work for your own research or private study.|
|Affiliation:||University of Stirling|
Computing Science and Mathematics
Computing Science - CSM Dept
Robert Gordon University
Mathematics - CSM Dept
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