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Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Biosafety standards for working with Crimean-Congo haemorrhagic fever virus (Forthcoming/Available Online)
Authors: Weidmann, Manfred
Avsic-Zupanc, Tatjana
Bino, Silvia
Bouloy, Michelle
Burt, Felicity
Sadegh, Chinikar
Christova, Iva
Dedushaj, Isuf
El-Sanousi, Ahmed A
Elaldi, Nazif
Hewson, Roger
Hufert, Frank T
Humolli, Isme
van, Vuren Petrus Jansen
Tufan, Zeliha K
Contact Email:
Issue Date: 21-Sep-2016
Publisher: Microbiology Society
Citation: Weidmann M, Avsic-Zupanc T, Bino S, Bouloy M, Burt F, Sadegh C, Christova I, Dedushaj I, El-Sanousi AA, Elaldi N, Hewson R, Hufert FT, Humolli I, van Vuren PJ & Tufan ZK Biosafety standards for working with Crimean-Congo haemorrhagic fever virus (Forthcoming/Available Online), Journal of General Virology.
Abstract: In countries from which Crimean-Congo haemorrhagic fever (CCHF) is absent, the causative virus CCHF virus (CCHFV) is classified as a hazard group 4 agent and handled in containment level 4. In contrast, most endemic countries out of necessity have had to perform diagnostic tests under biosafety level (BSL) -2 or -3 conditions. In particular, Turkey and several of the Balkan countries have safely processed more than 100000 samples over many years in BSL-2 laboratories. It is therefore advocated that biosafety requirements for CCHF diagnostic procedures should be revised, to allow the required tests to be performed under enhanced BSL-2 conditions with appropriate biosafety laboratory equipment and personal protective equipment used according to standardized protocols in the affected countries. Downgrading of CCHFV research work from Cl-4, BSL-4 to Cl-3, BSL-3 should also be considered.
Type: Journal Article
DOI Link:
Rights: This item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. Publisher policy allows this work to be made available in this repository. Published in Journal of General Virology by Microbiology Society. The original publication is available at:
Notes: Additional co-authors: Gülay Korukluoglu, Pieter Lyssen, Ali Mirazimi, Johan Neyts, Matthias Niedrig, Aykut Ozkul, Anna Papa, Janusz Paweska, Amadou A Sall, Connie S Schmaljohn, Robert Swanepoel, Yavuz Uyar, Friedemann Weber, Herve Zeller
Affiliation: Aquaculture
University of Ljubljana
Institute of Public Health, Albania
Institut Pasteur
National Institute for Communicable Diseases, South Africa
Institut Pasteur de Dakar
National Center for Infectious and Parasitic Diseases, Bulgaria
National Institute of Public Health, Kosovo
Cairo University
Cumhuriyet University, Turkey
Public Health England
University of Gottingen, Georg-August University
National Institute of Public Health, Kosovo
National Institute for Communicable Diseases, South Africa
Ministry of Health Republic of Turkey

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