|Appears in Collections:||Faculty of Health Sciences and Sport Book Chapters and Sections|
|Title:||The Future of Genomic Research in Athletic Performance and Adaptation to Training|
Collins, Malcolm R
Moran, Colin Neil
Britton, Steven L
de, Geus Eco
|Citation:||Wang G, Tanaka M, Eynon N, North K, Williams A, Collins MR, Moran CN, Britton SL, Fuku N, Ashley E, Klissouras V, Lucia A, Ahmetov I, de Geus E, Alsayrafi M & Pitsiladis Y (2016) The Future of Genomic Research in Athletic Performance and Adaptation to Training. In: Posthumus M, Collins M (ed.). Genetics and Sports, 2nd ed. Medicine and Sports Science, 61, Basel: Karger, pp. 55-67.|
|Series/Report no.:||Medicine and Sports Science, 61|
|Abstract:||Despite numerous attempts to discover genetic variants associated with elite athletic performance, an individual's trainability and injury predisposition, there has been limited progress to date. Past reliance on candidate gene studies focusing predominantly on genotyping a limited number of genetic variants in small, often heterogeneous cohorts has not generated results of practical significance. Hypothesis-free genome-wide approaches will in the future provide more comprehensive coverage and in-depth understanding of the biology underlying sports-related traits and related genetic mechanisms. Large, collaborative projects with sound experimental designs (e.g. clearly defined phenotypes, considerations and controls for sources of variability, and necessary replications) are required to produce meaningful results, especially when a hypothesis-free approach is used. It remains to be determined whether the novel approaches under current implementation will result in findings with real practical significance. This review will briefly summarize current and future directions in exercise genetics and genomics.|
|Rights:||The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.|
|Wang MSS 16 The future of genomic research in athletic performance and adaptation to training.pdf||133.21 kB||Adobe PDF||Under Embargo until 31/12/2999 Request a copy|
Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependant on the depositor still being contactable at their original email address.
This item is protected by original copyright
Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
If you believe that any material held in STORRE infringes copyright, please contact firstname.lastname@example.org providing details and we will remove the Work from public display in STORRE and investigate your claim.