Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/24051
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dc.contributor.authorMacnaughton, Lindsay Sen_UK
dc.contributor.authorWardle, Sophieen_UK
dc.contributor.authorWitard, Oliveren_UK
dc.contributor.authorMcGlory, Chrisen_UK
dc.contributor.authorHamilton, David Leeen_UK
dc.contributor.authorJeromson, Stewarten_UK
dc.contributor.authorLawrence, Claireen_UK
dc.contributor.authorWallis, Gareth Aen_UK
dc.contributor.authorTipton, Kevinen_UK
dc.date.accessioned2016-10-20T02:22:46Z-
dc.date.available2016-10-20T02:22:46Z-
dc.date.issued2016-08-10en_UK
dc.identifier.othere12893en_UK
dc.identifier.urihttp://hdl.handle.net/1893/24051-
dc.description.abstractThe currently accepted amount of protein required to achieve maximal stimulation of myofibrillar protein synthesis (MPS) following resistance exercise is 20–25g. However, the influence of lean body mass (LBM) on the response of MPS to protein ingestion is unclear. Our aim was to assess the influence of LBM, both total and the amount activated during exercise, on the maximal response of MPS to ingestion of 20 or 40g of whey protein following a bout of whole‐body resistance exercise. Resistance‐trained males were assigned to a group with lower LBM (≤65kg; LLBMn=15) or higher LBM (≥70kg; HLBMn=15) and participated in two trials in random order. MPS was measured with the infusion of13C6‐phenylalanine tracer and collection of muscle biopsies following ingestion of either 20 or 40g protein during recovery from a single bout of whole‐body resistance exercise. A similar response of MPS during exercise recovery was observed between LBM groups following protein ingestion (20g – LLBM: 0.048±0.018%·h−1; HLBM: 0.051±0.014%·h−1; 40g – LLBM: 0.059±0.021%·h−1; HLBM: 0.059±0.012%·h−1). Overall (groups combined), MPS was stimulated to a greater extent following ingestion of 40g (0.059±0.020%·h−1) compared with 20g (0.049±0.020%·h−1;P=0.005) of protein. Our data indicate that ingestion of 40g whey protein following whole‐body resistance exercise stimulates a greater MPS response than 20g in young resistance‐trained men. However, with the current doses, the total amount of LBM does not seem to influence the response.en_UK
dc.language.isoenen_UK
dc.publisherAmerican Physiological Societyen_UK
dc.relationMacnaughton LS, Wardle S, Witard O, McGlory C, Hamilton DL, Jeromson S, Lawrence C, Wallis GA & Tipton K (2016) The response of muscle protein synthesis following whole-body resistance exercise is greater following 40 g than 20 g of ingested whey protein. Physiological Reports, 4, Art. No.: e12893. https://doi.org/10.14814/phy2.12893en_UK
dc.rights© 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.en_UK
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_UK
dc.titleThe response of muscle protein synthesis following whole-body resistance exercise is greater following 40 g than 20 g of ingested whey proteinen_UK
dc.typeJournal Articleen_UK
dc.identifier.doi10.14814/phy2.12893en_UK
dc.identifier.pmid27511985en_UK
dc.citation.jtitlePhysiological Reportsen_UK
dc.citation.issn2051-817Xen_UK
dc.citation.volume4en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emailk.d.tipton@stir.ac.uken_UK
dc.citation.date10/08/2016en_UK
dc.contributor.affiliationUniversity of Stirlingen_UK
dc.contributor.affiliationSporten_UK
dc.contributor.affiliationSporten_UK
dc.contributor.affiliationMcMaster Universityen_UK
dc.contributor.affiliationSporten_UK
dc.contributor.affiliationSporten_UK
dc.contributor.affiliationGlaxoSmithKlineen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationSporten_UK
dc.identifier.isiWOS:000383441900015en_UK
dc.identifier.scopusid2-s2.0-84982126542en_UK
dc.identifier.wtid552664en_UK
dc.contributor.orcid0000-0002-5875-8397en_UK
dc.contributor.orcid0000-0002-5620-4788en_UK
dc.contributor.orcid0000-0002-6545-8122en_UK
dc.date.accepted2016-07-20en_UK
dcterms.dateAccepted2016-07-20en_UK
dc.date.filedepositdate2016-08-17en_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorMacnaughton, Lindsay S|en_UK
local.rioxx.authorWardle, Sophie|en_UK
local.rioxx.authorWitard, Oliver|0000-0002-5875-8397en_UK
local.rioxx.authorMcGlory, Chris|en_UK
local.rioxx.authorHamilton, David Lee|0000-0002-5620-4788en_UK
local.rioxx.authorJeromson, Stewart|en_UK
local.rioxx.authorLawrence, Claire|en_UK
local.rioxx.authorWallis, Gareth A|en_UK
local.rioxx.authorTipton, Kevin|0000-0002-6545-8122en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2016-08-17en_UK
local.rioxx.licencehttp://creativecommons.org/licenses/by/4.0/|2016-08-17|en_UK
local.rioxx.filenamemacnaughton 16 LPMMPS PhysRep.pdfen_UK
local.rioxx.filecount1en_UK
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