Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/22730
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dc.contributor.authorRobertson, Tonyen_UK
dc.contributor.authorBatty, G Daviden_UK
dc.contributor.authorDer, Geoffen_UK
dc.contributor.authorFenton, Candidaen_UK
dc.contributor.authorShiels, Paul Gen_UK
dc.contributor.authorBenzeval, Michaelaen_UK
dc.date.accessioned2016-01-14T23:41:40Z-
dc.date.available2016-01-14T23:41:40Z-
dc.date.issued2013en_UK
dc.identifier.urihttp://hdl.handle.net/1893/22730-
dc.description.abstractIt has been hypothesized that one way in which lower socioeconomic status (SES) affects health is by increasing the rate of biological aging. A widely used marker of biological aging is telomere length. Telomeres are structures at the ends of chromosomes that erode with increasing cell proliferation and genetic damage. We aimed to identify, through systematic review and meta-analysis, whether lower SES (greater deprivation) is associated with shorter telomeres. Thirty-one articles, including 29 study populations, were identified. We conducted 3 meta-analyses to compare the telomere lengths of persons of high and low SES with regard to contemporaneous SES (12 study populations from 10 individual articles), education (15 study populations from 14 articles), and childhood SES (2 study populations from 2 articles). For education, there was a significant difference in telomere length between persons of high and low SES in a random-effects model (standardized mean difference (SMD) = 0.060, 95% confidence interval (CI): 0.002, 0.118; P = 0.042), although a range of sensitivity analyses weakened this association. There was no evidence for an association between telomere length and contemporaneous SES (SMD = 0.104, 95% CI: -0.027, 0.236; P = 0.119) or childhood SES (SMD = -0.037, 95% CI: -0.143, 0.069; P = 0.491). These results suggest weak evidence for an association between SES (as measured by education) and biological aging (as measured by telomere length), although there was a lack of consistent findings across the SES measures investigated here.en_UK
dc.language.isoenen_UK
dc.publisherOxford University Pressen_UK
dc.relationRobertson T, Batty GD, Der G, Fenton C, Shiels PG & Benzeval M (2013) Is socioeconomic status associated with biological aging as measured by telomere length?. Epidemiologic Reviews, 35 (1), pp. 98-111. https://doi.org/10.1093/epirev/mxs001en_UK
dc.rights© The Author 2012. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.en_UK
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en_UK
dc.subjectbiological agingen_UK
dc.subjectreview, systematicen_UK
dc.subjectsocioeconomic statusen_UK
dc.subjecttelomere lengthen_UK
dc.titleIs socioeconomic status associated with biological aging as measured by telomere length?en_UK
dc.typeJournal Articleen_UK
dc.identifier.doi10.1093/epirev/mxs001en_UK
dc.identifier.pmid23258416en_UK
dc.citation.jtitleEpidemiologic Reviewsen_UK
dc.citation.issn1478-6729en_UK
dc.citation.issn0193-936Xen_UK
dc.citation.volume35en_UK
dc.citation.issue1en_UK
dc.citation.spage98en_UK
dc.citation.epage111en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emailtony.robertson@stir.ac.uken_UK
dc.citation.date20/12/2012en_UK
dc.contributor.affiliationHS - Management and Support - LEGACYen_UK
dc.contributor.affiliationUniversity of Edinburghen_UK
dc.contributor.affiliationUniversity of Birminghamen_UK
dc.contributor.affiliationUniversity of Glasgowen_UK
dc.contributor.affiliationUniversity of Glasgowen_UK
dc.contributor.affiliationUniversity of Glasgowen_UK
dc.identifier.isiWOS:000315703400009en_UK
dc.identifier.scopusid2-s2.0-84874467922en_UK
dc.identifier.wtid580561en_UK
dc.contributor.orcid0000-0002-1962-5874en_UK
dc.date.accepted2012-08-10en_UK
dcterms.dateAccepted2012-08-10en_UK
dc.date.filedepositdate2016-01-14en_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorRobertson, Tony|0000-0002-1962-5874en_UK
local.rioxx.authorBatty, G David|en_UK
local.rioxx.authorDer, Geoff|en_UK
local.rioxx.authorFenton, Candida|en_UK
local.rioxx.authorShiels, Paul G|en_UK
local.rioxx.authorBenzeval, Michaela|en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2016-01-14en_UK
local.rioxx.licencehttp://creativecommons.org/licenses/by-nc/4.0/|2016-01-14|en_UK
local.rioxx.filenamerobertson (2013) epi rev - telomere x ses review.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source0193-936Xen_UK
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