Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/22287
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Molecular phylogeography of tick-borne encephalitis virus in central Europe
Authors: Weidmann, Manfred
Frey, Stefan
Freire, Caio C M
Essbauer, Sandra
Ruzek, Daniel
Klempa, Boris
Zubrikova, Dana
Vogerl, Maria
Pfeffer, Martin
Hufert, Frank T
Zanotto, Paolo M D A
Dobler, Gerhard
Contact Email: m.w.weidmann@stir.ac.uk
Issue Date: Sep-2013
Publisher: Society for General Microbiology
Citation: Weidmann M, Frey S, Freire CCM, Essbauer S, Ruzek D, Klempa B, Zubrikova D, Vogerl M, Pfeffer M, Hufert FT, Zanotto PMAD & Dobler G (2013) Molecular phylogeography of tick-borne encephalitis virus in central Europe, Journal of General Virology, 94 (Part 9), pp. 2129-2139.
Abstract: In order to obtain a better understanding of tick-borne encephalitis virus (TBEV) strain movements in central Europe the E gene sequences of 102 TBEV strains collected from 1953 to 2011 at 38 sites in the Czech Republic, Slovakia, Austria and Germany were determined. Bayesian analysis suggests a 350-year history of evolution and spread in central Europe of two main lineages, A and B. In contrast to the east to west spread at the Eurasian continent level, local central European spreading patterns suggest historic west to east spread followed by more recent east to west spread. The phylogenetic and network analyses indicate TBEV ingressions from the Czech Republic and Slovakia into Germany via landscape features (Danube river system), biogenic factors (birds, red deer) and anthropogenic factors. The identification of endemic foci showing local genetic diversity is of paramount importance to the field as these will be a prerequisite for in-depth analysis of focal TBEV maintenance and long-distance TBEV spread.
Type: Journal Article
URI: http://hdl.handle.net/1893/22287
DOI Link: http://dx.doi.org/10.1099/vir.0.054478-0
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: Aquaculture
Bunderwehr Institute for Microbiology
University of Sao Paulo
Bunderwehr Institute for Microbiology
Czech Academy of Sciences
Slovak Academy of Sciences
Slovak Academy of Sciences
Ludwig Maximilian University, Germany
University Leipzig
University of Gottingen, Georg-August University
University of Sao Paulo
Bunderwehr Institute for Microbiology

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