Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/21418
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Investigating the underlying mechanisms of temperature-related skin diseases in Atlantic salmon, Salmo salar L., as measured by quantitative histology, skin transcriptomics and composition (Forthcoming/Available Online)
Authors: Jensen, Linda
Boltana, Sebastian
Obach, Alex
McGurk, Charles
Waagbo, Rune
MacKenzie, Simon
Contact Email: simon.mackenzie@stir.ac.uk
Keywords: Salmo salar
skin histology
skin composition
mucosal immunity
Issue Date: 1-Oct-2014
Publisher: Wiley-Blackwell
Citation: Jensen L, Boltana S, Obach A, McGurk C, Waagbo R & MacKenzie S Investigating the underlying mechanisms of temperature-related skin diseases in Atlantic salmon, Salmo salar L., as measured by quantitative histology, skin transcriptomics and composition (Forthcoming/Available Online), Journal of Fish Diseases.
Abstract: Skin integrity is recognized as of vital consideration for both animal welfare and final product quality of farmed fish. This study examines the effects of three different rearing temperatures (4, 10 and 16°C) on the skin of healthy Atlantic salmon post-smolts. Changes in skin condition were assessed by the means of skin composition analyses, quantitative histology assessments and transcriptome analysis. Level of protein, vitamin C and vitamin E was significantly higher at 16°C compared with 4°C. Quantitative histology measurements showed that the epidermal thickness decreased from low to high temperature, whereas the epidermal area comprising mucous cells increased. The difference was only significant between 4 and 16°C. Both high and low temperature exhibited significant changes in the skin transcriptome. A number of immune-related transcripts responded at both temperatures. Contrary to well-described immunosuppressive effects of low water temperature on systemic immunity, a subtle increase in skin-mediated immunity was observed, suggesting a pre-activation of the mucosal system at 4°C. Upregulation of a number of heat-shock proteins correlating with a decrease in epidermal thickness suggested a stress response in the skin at high temperature. The results demonstrate distinctive temperature-related effects on the skin of Atlantic salmon.
Type: Journal Article
URI: http://hdl.handle.net/1893/21418
DOI Link: http://dx.doi.org/10.1111/jfd.12314
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: Skretting Aquaculture Research Centre
Aquaculture
Skretting Aquaculture Research Centre
Skretting Aquaculture Research Centre
Skretting Aquaculture Research Centre
Complex Systems

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