Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/21348
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Effect of the coexistence on the replication of striped jack nervous necrosis virus (SJNNV) and red-spotted grouper nervous necrosis virus (RGNNV) using an in vitro approach
Authors: Lopez, Jimena Benjamin
Garcia-Rosado, Esther
Infante, Carlos
Castro, Dolores
Borrego, Juan J
Alonso, Maria del Carmen
Contact Email: benjamin.lopez-jimena1@stir.ac.uk
Issue Date: Oct-2014
Publisher: Wiley-Blackwell
Citation: Lopez Jimena B, Garcia-Rosado E, Infante C, Castro D, Borrego JJ & Alonso MdC (2014) Effect of the coexistence on the replication of striped jack nervous necrosis virus (SJNNV) and red-spotted grouper nervous necrosis virus (RGNNV) using an in vitro approach, Journal of Applied Ichthyology, 30 (5), pp. 916-922.
Abstract: Viral nervous necrosis virus (VNNV) is the aetiological agent of viral nervous necrosis (VNN), a widespread disease affecting different marine and freshwater fish species. Striped jack nervous necrosis virus (SJNNV) and red-spotted grouper nervous necrosis virus (RGNNV) are the only genotypes of the Betanodavirus genus recorded in the Iberian Peninsula to date, but a high percentage of wild specimens simultaneously carrying both genotypes has been recently reported. The coexistence of the two viruses may affect the course of both viral infections. In the present study, viral genome quantification by two absolute real-time PCR protocols has been performed to characterise the effect of the RGNNV-SJNNV coexistence (coinfection and superinfection) on the replication of each genotype in E-11 cells. This is the first study showing the effect of the coexistence on the viral replication of two genotypes within the Betanodavirus genus. The results obtained in vitro showed the partial inhibition of SJNNV replication by the coexistence with RGNNV, whereas RGNNV replication was favoured in coinfection or superinfection with SJNNV.
Type: Journal Article
URI: http://hdl.handle.net/1893/21348
DOI Link: http://dx.doi.org/10.1111/jai.12473
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: Aquaculture
University of Malaga
Centro IFAPA, Spain
University of Malaga
University of Malaga
University of Malaga

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