Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/20620
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dc.contributor.authorFernando, Malinduen_UK
dc.contributor.authorCrowther, Roberten_UK
dc.contributor.authorPappas, Eliseen_UK
dc.contributor.authorLazzarini, Peteren_UK
dc.contributor.authorCunningham, Margareten_UK
dc.contributor.authorSangla, Kunwarjiten_UK
dc.contributor.authorButtner, Petraen_UK
dc.contributor.authorGolledge, Jonathanen_UK
dc.date.accessioned2014-09-25T23:36:03Z-
dc.date.available2014-09-25T23:36:03Z-
dc.date.issued2014-06en_UK
dc.identifier.othere99050en_UK
dc.identifier.urihttp://hdl.handle.net/1893/20620-
dc.description.abstractAims: Elevated dynamic plantar pressures are a consistent finding in diabetes patients with peripheral neuropathy with implications for plantar foot ulceration. This meta-analysis aimed to compare the plantar pressures of diabetes patients that had peripheral neuropathy and those with neuropathy with active or previous foot ulcers. Methods: Published articles were identified from Medline via OVID, CINAHL, SCOPUS, INFORMIT, Cochrane Central EMBASE via OVID and Web of Science via ISI Web of Knowledge bibliographic databases. Observational studies reporting barefoot dynamic plantar pressure in adults with diabetic peripheral neuropathy, where at least one group had a history of plantar foot ulcers were included. Interventional studies, shod plantar pressure studies and studies not published in English were excluded. Overall mean peak plantar pressure (MPP) and pressure time integral (PTI) were primary outcomes. The six secondary outcomes were MPP and PTI at the rear foot, mid foot and fore foot. The protocol of the meta-analysis was published with PROPSERO, (registration number CRD42013004310). Results: Eight observational studies were included. Overall MPP and PTI were greater in diabetic peripheral neuropathy patients with foot ulceration compared to those without ulceration (standardised mean difference 0.551, 95% CI 0.290-0.811, p<0.001; and 0.762, 95% CI 0.303-1.221, p = 0.001, respectively). Sub-group analyses demonstrated no significant difference in MPP for those with neuropathy with active ulceration compared to those without ulcers. A significant difference in MPP was found for those with neuropathy with a past history of ulceration compared to those without ulcers; (0.467, 95% CI 0.181- 0.753, p = 0.001). Statistical heterogeneity between studies was moderate. Conclusions: Plantar pressures appear to be significantly higher in patients with diabetic peripheral neuropathy with a history of foot ulceration compared to those with diabetic neuropathy without a history of ulceration. More homogenous data is needed to confirm these findings.en_UK
dc.language.isoenen_UK
dc.publisherPublic Library of Scienceen_UK
dc.relationFernando M, Crowther R, Pappas E, Lazzarini P, Cunningham M, Sangla K, Buttner P & Golledge J (2014) Plantar Pressure in Diabetic Peripheral Neuropathy Patients with Active Foot Ulceration, Previous Ulceration and No History of Ulceration: A Meta-Analysis of Observational Studies. PLoS ONE, 9 (6), Art. No.: e99050. https://doi.org/10.1371/journal.pone.0099050en_UK
dc.rights© 2014 Fernando et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_UK
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_UK
dc.titlePlantar Pressure in Diabetic Peripheral Neuropathy Patients with Active Foot Ulceration, Previous Ulceration and No History of Ulceration: A Meta-Analysis of Observational Studiesen_UK
dc.typeJournal Articleen_UK
dc.identifier.doi10.1371/journal.pone.0099050en_UK
dc.citation.jtitlePLoS ONEen_UK
dc.citation.issn1932-6203en_UK
dc.citation.volume9en_UK
dc.citation.issue6en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emailmargaret.cunningham@stir.ac.uken_UK
dc.contributor.affiliationJames Cook Universityen_UK
dc.contributor.affiliationJames Cook Universityen_UK
dc.contributor.affiliationJames Cook Universityen_UK
dc.contributor.affiliationQueensland University of Technologyen_UK
dc.contributor.affiliationPsychologyen_UK
dc.contributor.affiliationQueensland Healthen_UK
dc.contributor.affiliationJames Cook Universityen_UK
dc.contributor.affiliationJames Cook Universityen_UK
dc.identifier.isiWOS:000340947700054en_UK
dc.identifier.scopusid2-s2.0-84902578309en_UK
dc.identifier.wtid624551en_UK
dc.contributor.orcid0000-0002-5850-9825en_UK
dcterms.dateAccepted2014-06-30en_UK
dc.date.filedepositdate2014-07-15en_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorFernando, Malindu|en_UK
local.rioxx.authorCrowther, Robert|en_UK
local.rioxx.authorPappas, Elise|en_UK
local.rioxx.authorLazzarini, Peter|en_UK
local.rioxx.authorCunningham, Margaret|0000-0002-5850-9825en_UK
local.rioxx.authorSangla, Kunwarjit|en_UK
local.rioxx.authorButtner, Petra|en_UK
local.rioxx.authorGolledge, Jonathan|en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2014-07-15en_UK
local.rioxx.licencehttp://creativecommons.org/licenses/by/4.0/|2014-07-15|en_UK
local.rioxx.filenameFernando 2014.pdfen_UK
local.rioxx.filecount1en_UK
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