Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/18271
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Genetic characterization of Tribec virus and Kemerovo virus, two tick-transmitted human-pathogenic Orbiviruses
Authors: Dilcher, Meik
Hasib, Lekbira
Lechner, Marcus
Wieseke, Nicolas
Middendorf, Martin
Marz, Manja
Koch, Andrea
Spiegel, Martin
Dobler, Gerhard
Hufert, Frank T
Weidmann, Manfred
Contact Email: m.w.weidmann@stir.ac.uk
Keywords: Tribec virus
Kemerovo virus
Reovirus
Orbivirus
Co-evolution
Issue Date: 5-Feb-2012
Publisher: Elsevier
Citation: Dilcher M, Hasib L, Lechner M, Wieseke N, Middendorf M, Marz M, Koch A, Spiegel M, Dobler G, Hufert FT & Weidmann M (2012) Genetic characterization of Tribec virus and Kemerovo virus, two tick-transmitted human-pathogenic Orbiviruses, Virology, 423 (1), pp. 68-76.
Abstract: We determined the complete genome sequences of Tribeč virus (TRBV) and Kemerovo virus (KEMV), two tick-transmitted Orbiviruses that can cause diseases of the central nervous system and that are currently classified into the Great Island virus serogroup. VP2 proteins of TRBV and KEMV show very low sequence similarity to the homologous VP4 protein of tick-transmitted Great Island virus (GIV). The new sequence data support previous serological classification of these Orbiviruses into the Kemerovo serogroup, which is different from the Great Island virus serogroup. Genome segment 9 of TRBV and KEMV encodes several overlapping ORF's in the + 1 reading frame relative to VP6(Hel). A co-phylogenetic analysis indicates a host switch from insect-borne Orbiviruses toward Ixodes species, which is in disagreement with previously published data.
Type: Journal Article
URI: http://hdl.handle.net/1893/18271
DOI Link: http://dx.doi.org/10.1016/j.virol.2011.11.020
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: University of Gottingen, Georg-August University
University of Gottingen, Georg-August University
Philipps University of Marburg
University Leipzig
University Leipzig
Philipps University of Marburg
University of Gottingen, Georg-August University
University of Gottingen, Georg-August University
Bunderwehr Institute for Microbiology
University of Gottingen, Georg-August University
Aquaculture

Files in This Item:
File Description SizeFormat 
Virology 2012.pdf947.55 kBAdobe PDFUnder Embargo until 31/12/2999     Request a copy

Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependant on the depositor still being contactable at their original email address.

This item is protected by original copyright



Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.