Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/18267
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Characterization of a sandfly fever Sicilian virus isolated during a sandfly fever epidemic in Turkey
Authors: Carhan, Ahmet
Uyar, Yavuz
Ozkaya, Etem
Ertek, Mustafa
Dobler, Gerhard
Dilcher, Meik
Wang, Yongjie
Spiegel, Martin
Hufert, Frank T
Weidmann, Manfred
Contact Email: m.w.weidmann@stir.ac.uk
Keywords: Sandfly fever virus
Phlebovirus
Diagnostics for Phleboviruses
Phlebotumus
Issue Date: Aug-2010
Publisher: Elsevier
Citation: Carhan A, Uyar Y, Ozkaya E, Ertek M, Dobler G, Dilcher M, Wang Y, Spiegel M, Hufert FT & Weidmann M (2010) Characterization of a sandfly fever Sicilian virus isolated during a sandfly fever epidemic in Turkey, Journal of Clinical Virology, 48 (4), pp. 264-269.
Abstract: Background: Phleboviruses cause sandfly fever but isolates are rare. Objectives: To analyse samples from concurrent outbreaks of suspected sandfly fever in the Mediterranean provinces of Adana, Izmir and the central province of Ankara, Turkey. Study design: Samples from acute cases were analysed by immunofluorescence assay (IFA). Virus isolation was attempted and pyrosequencing performed. Results: In IFA 38% of 106 samples tested scored IgM positive for sandfly fever Sicillian virus (SFSV), 12% for SFSV/sandfly fever Cyprus Virus (SFCV) and only 4% for SFCV. A sandfly fever Sicilian type virus designated sandfly fever Turkey virus (SFTV) was isolated. The S-segment sequence of SFTV had a homology of 98% to that of SFCV. The M-segment sequence showed a 91.1% homology to the only SFSV sequence available. The L-segment sequence showed a homology of 58% and 60.3% to Toscana virus and Rift Valley Fever virus sequences, a partial 201 nt sequence showed 95.5% homology to the SFSV Sabin strain. Conclusion: A new phlebovirus related to sandfly fever Sicilian virus, SFTV was isolated and characterized from acute patient material. The sandfly fever Sicilian virus activity seems to be changing in Turkey. Entomological studies are needed.
Type: Journal Article
URI: http://hdl.handle.net/1893/18267
DOI Link: http://dx.doi.org/10.1016/j.jcv.2010.05.011
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: Refik Saydam National Public Health Agency
Refik Saydam National Public Health Agency
Refik Saydam National Public Health Agency
Refik Saydam National Public Health Agency
Bunderwehr Institute for Microbiology
University of Gottingen, Georg-August University
University of Gottingen, Georg-August University
University of Gottingen, Georg-August University
University of Gottingen, Georg-August University
Aquaculture

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