Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/16521
Appears in Collections:Computing Science and Mathematics Book Chapters and Sections
Peer Review Status: Refereed
Title: A novel clinical expert system for chest pain risk assessment
Authors: Farooq, Kamran
Hussain, Amir
Atassi, Hicham
Leslie, Stephen
Eckl, Chris
MacRae, Calum
Slack, Warner
Contact Email: amir.hussain@stir.ac.uk
Editors: Liu, D
Alippi, C
Zhao, D
Hussain, A
Citation: Farooq K, Hussain A, Atassi H, Leslie S, Eckl C, MacRae C & Slack W (2013) A novel clinical expert system for chest pain risk assessment In: Liu D, Alippi C, Zhao D, Hussain A (ed.) Advances in Brain Inspired Cognitive Systems: 6th International Conference, BICS 2013, Beijing, China, June 9-11, 2013. Proceedings, Berlin Heidelberg: Springer. 6th International Conference on Brain Inspired Cognitive Systems, BICS 2013, 9.6.2012 - 11.6.2013, Beijing, China, pp. 296-307.
Keywords: RACPC risk assessment
Chest pain decision support system
Clinical decision support system for chest pain based on NICE Guidelines
Issue Date: 2013
Publisher: Springer
Series/Report no.: Lecture Notes in Computer Science, 7888
Abstract: Rapid access chest pain clinics (RACPC) enable clinical risk assessment, investigation and arrangement of a treatment plan for chest pain patients without a long waiting list. RACPC Clinicians often experience difficulties in the diagnosis of chest pain due to the inherent complexity of the clinical process and lack of comprehensive automated diagnostic tools. To date, various risk assessment models have been proposed, inspired by the National Institute of Clinical Excellence (NICE) guidelines to provide clinical decision support mechanism in chest pain diagnosis. The aim of this study is to help improve the performance of RACPC, specifically from the clinical decision support perspective. The study cohort comprises of 632 patients suspected of cardiac chest pain. A retrospective data analysis of the clinical studies evaluating 14 risk factors for chest pain patients was performed for the development of RACPC specific risk assessment models to distinguish between cardiac and non cardiac chest pain. In the first phase, a novel binary classification model was developed using a Decision Tree algorithm in conjunction with forward and backward selection wrapping techniques. Secondly, a logistic regression model was trained using all of the given variables combined with forward and backward feature selection techniques to identify the most significant features. The new models have resulted in very good predictive power, demonstrating general performance improvement compared to a state-of-the-art prediction model.
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Type: Conference Paper
URI: http://hdl.handle.net/1893/16521
URL: http://link.springer.com/chapter/10.1007/978-3-642-38786-9_34#
Affiliation: Computing Science - CSM Dept
Computing Science - CSM Dept
University of Stirling
NHS Highland
Sitekit
Brigham and Women's Hospital
Harvard University

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