Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/12177
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles
Peer Review Status: Refereed
Title: PASAT performance and the pattern of uptake of 99mTc-exametazime in brain estimated with single photon emission tomography
Authors: Deary, Ian
Ebmeier, Klaus P
MacLeod, Kenneth M
Dougall, Nadine
Hepburn, David A
Frier, Brian M
Goodwin, Guy M
Contact Email: nadine.dougall@stir.ac.uk
Keywords: PASAT
Single photon emission tomography
Cingulate cortex
Attention
Issue Date: Sep-1994
Publisher: Elsevier
Citation: Deary I, Ebmeier KP, MacLeod KM, Dougall N, Hepburn DA, Frier BM & Goodwin GM (1994) PASAT performance and the pattern of uptake of 99mTc-exametazime in brain estimated with single photon emission tomography, Biological Psychology, 38 (1), pp. 1-18.
Abstract: The effect of the paced auditory serial addition test (PASAT) on the regional uptake of 99mTc-exametazime was determined by single photon emission computed tomography. Twenty insulin-treated diabetic outpatients were scanned at rest and during the performance of the PASAT task using split-dose injection of tracer. When resting and activation scans were compared there were significant decreases in tracer uptake in the right anterior cingulate and left posterior cingulate areas during PASAT activation. The findings are compared with previous studies which had implicated the anterior cingulate area in the mechanisms of attention in humans and other animals. The potentially confounding role of anxiety during attentional tasks is discussed.
Type: Journal Article
URI: http://hdl.handle.net/1893/12177
DOI Link: http://dx.doi.org/10.1016/0301-0511(94)90046-9
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: University of Edinburgh
Royal Edinburgh Hospital
Royal Infirmary of Edinburgh
NMAHP Research
Royal Infirmary of Edinburgh
Royal Infirmary of Edinburgh
Royal Edinburgh Hospital

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