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Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/1148
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dc.contributor.authorCnaani, Avneren_UK
dc.contributor.authorLee, Bo-Youngen_UK
dc.contributor.authorZilberman, Noamen_UK
dc.contributor.authorOzouf-Costaz, Catherineen_UK
dc.contributor.authorHulata, Gideonen_UK
dc.contributor.authorRon, Michaen_UK
dc.contributor.authorD’Hont, Angeliqueen_UK
dc.contributor.authorBaroiller, Jean-Francoisen_UK
dc.contributor.authorD’Cotta, Helenaen_UK
dc.contributor.authorPenman, Daviden_UK
dc.contributor.authorTomasino, Elizabethen_UK
dc.contributor.authorCoutanceau, Jean-Pierreen_UK
dc.contributor.authorPepey, Elodieen_UK
dc.contributor.authorShirak, Andreyen_UK
dc.contributor.authorKocher, Thomas Den_UK
dc.date.accessioned2017-09-23T00:15:47Z-
dc.date.available2017-09-23T00:15:47Zen_UK
dc.date.issued2008-04en_UK
dc.identifier.urihttp://hdl.handle.net/1893/1148-
dc.description.abstractWe identified DNA markers linked to sex determining genes in six closely related species of tilapiine fishes. The mode of sex determination differed among species. In Oreochromis karongae and Tilapia mariae the sex-determining locus is on linkage group (LG) 3 and the female is heterogametic (WZ-ZZ system). In O. niloticus and T. zillii the sex-determining locus is on LG1 and the male is heterogametic (XX-XY system). A more complex pattern was observed in O. aureus and O. mossambicus, in which markers on both LG1 and LG3 were associated with sex. We found evidence for sex-linked lethal effects on LG1, as well as interactions between loci in the two linkage groups. Comparison of genetic and physical maps demonstrated a broad region of recombination suppression harboring the sex-determining locus on LG3. Sex-specific recombination suppression was found in the female heterogametic sex. Sequence analysis showed the accumulation of repetitive elements in this region. Phylogenetic analysis suggests that at least two transitions in the mode of sex determination have occurred in this clade. This variation in sex determination mechanisms among closely related species makes tilapias an excellent model system for studying the evolution of sex chromosomes in vertebrates.en_UK
dc.language.isoenen_UK
dc.publisherKargeren_UK
dc.relationCnaani A, Lee B, Zilberman N, Ozouf-Costaz C, Hulata G, Ron M, D’Hont A, Baroiller J, D’Cotta H, Penman D, Tomasino E, Coutanceau J, Pepey E, Shirak A & Kocher TD (2008) Genetics of sex determination in tilapiine species. Sexual Development, 2 (1), pp. 43-54. https://doi.org/10.1159/000117718en_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author; you can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.rights.urihttp://www.rioxx.net/licenses/under-embargo-all-rights-reserveden_UK
dc.subjectCichlidaeen_UK
dc.subjectheterogametic sexen_UK
dc.subjectinversionen_UK
dc.subjectOreochromisen_UK
dc.subjectrecombination suppressionen_UK
dc.subjectsex chromosomeen_UK
dc.subjectsex determinationen_UK
dc.subjectTilapiaen_UK
dc.subjectTilapiaen_UK
dc.subjectTilapia Geneticsen_UK
dc.subjectSex determination, Geneticen_UK
dc.subjectSex Chromosomes geneticsen_UK
dc.titleGenetics of sex determination in tilapiine speciesen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31en_UK
dc.rights.embargoreason[Cnaani et al 2008 Sex Dev sex det in tilapias.pdf] I do not have the final authors' version of this article. The document submitted is the final journal article, and the embargo should be permanent for copyright reasons. Anyone wanting a copy can request it from me. The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.identifier.doi10.1159/000117718en_UK
dc.identifier.pmid18418034en_UK
dc.citation.jtitleSexual Developmenten_UK
dc.citation.issn1661-5433en_UK
dc.citation.issn1661-5425en_UK
dc.citation.volume2en_UK
dc.citation.issue1en_UK
dc.citation.spage43en_UK
dc.citation.epage54en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emaildjp1@stir.ac.uken_UK
dc.contributor.affiliationVirginia Polytechnic Institute And State Universityen_UK
dc.contributor.affiliationUniversity of Marylanden_UK
dc.contributor.affiliationAgricultural Research Organization (ARO)en_UK
dc.contributor.affiliationMuseum National d’Histoire Naturelleen_UK
dc.contributor.affiliationAgricultural Research Organization (ARO)en_UK
dc.contributor.affiliationAgricultural Research Organization (ARO)en_UK
dc.contributor.affiliationCIRADen_UK
dc.contributor.affiliationCIRADen_UK
dc.contributor.affiliationCIRADen_UK
dc.contributor.affiliationInstitute of Aquacultureen_UK
dc.contributor.affiliationCornell Universityen_UK
dc.contributor.affiliationMuseum National d’Histoire Naturelleen_UK
dc.contributor.affiliationCIRADen_UK
dc.contributor.affiliationAgricultural Research Organization (ARO)en_UK
dc.contributor.affiliationUniversity of Marylanden_UK
dc.identifier.isiWOS:000255175600006en_UK
dc.identifier.scopusid2-s2.0-42349117351en_UK
dc.identifier.wtid836076en_UK
dc.contributor.orcid0000-0001-8608-6631en_UK
dc.date.accepted2007-10-22en_UK
dcterms.dateAccepted2007-10-22en_UK
dc.date.filedepositdate2009-05-05en_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorCnaani, Avner|en_UK
local.rioxx.authorLee, Bo-Young|en_UK
local.rioxx.authorZilberman, Noam|en_UK
local.rioxx.authorOzouf-Costaz, Catherine|en_UK
local.rioxx.authorHulata, Gideon|en_UK
local.rioxx.authorRon, Micha|en_UK
local.rioxx.authorD’Hont, Angelique|en_UK
local.rioxx.authorBaroiller, Jean-Francois|en_UK
local.rioxx.authorD’Cotta, Helena|en_UK
local.rioxx.authorPenman, David|0000-0001-8608-6631en_UK
local.rioxx.authorTomasino, Elizabeth|en_UK
local.rioxx.authorCoutanceau, Jean-Pierre|en_UK
local.rioxx.authorPepey, Elodie|en_UK
local.rioxx.authorShirak, Andrey|en_UK
local.rioxx.authorKocher, Thomas D|en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2999-12-31en_UK
local.rioxx.licencehttp://www.rioxx.net/licenses/under-embargo-all-rights-reserved||en_UK
local.rioxx.filenameCnaani et al 2008 Sex Dev sex det in tilapias.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source1661-5425en_UK
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