Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/10160
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Histological damage and inflammatory response elicited by Monobothrium wageneri (Cestoda) in the intestine of Tinca tinca (Cyprinidae)
Authors: Dezfuli, Bahram S
Giari, Luisa
Squerzanti, Samantha
Lui, Alice
Lorenzoni, Massimo
Sakalli, Sidika
Shinn, Andrew
Contact Email: aps1@stir.ac.uk
Keywords: Caryophyllidean
tapeworm
mucous cells
granulocytes
immune response
Issue Date: Dec-2011
Publisher: BioMed Central Ltd
Citation: Dezfuli BS, Giari L, Squerzanti S, Lui A, Lorenzoni M, Sakalli S & Shinn A (2011) Histological damage and inflammatory response elicited by Monobothrium wageneri (Cestoda) in the intestine of Tinca tinca (Cyprinidae), Parasites and Vectors, 4, p. 225.
Abstract: Background: Among the European cyprinids, tench, Tinca tinca (L.), and the pathological effects their cestodes may effect, have received very little or no attention. Most literature relating to Monobothrium wageneri Nybelin, 1922, a common intestinal cestode of tench, for example, has focused on aspects of its morphology rather than on aspects of the host-parasite interaction. Results: Immunopathological and ultrastructural studies were conducted on the intestines of 28 tench, collected from Lake Piediluco, of which 16 specimens harboured tight clusters of numerous M. wageneri attached to the intestinal wall. The infection was associated with the degeneration of the mucosal layer and the formation of raised inflammatory swelling surrounding the worms. At the site of infection, the number of granulocytes in the intestine of T. tinca was significantly higher than the number determined 1 cm away from the site of infection or the number found in uninfected fish. Using transmission electron microscopy, mast cells and neutrophils were frequently observed in close proximity to, and inside, the intestinal capillaries; often these cells were in contact with the cestode tegument. At the host-parasite interface, no secretion from the parasite's tegument was observed. Intense degranulation of the mast cells was seen within the submucosa and lamina muscularis, most noticeably at sites close to the tegument of the scolex. In some instances, rodlet cells were encountered in the submucosa. In histological sections, hyperplasia of the mucous cells, notably those giving an alcian blue positive reaction, were evident in the intestinal tissues close to the swelling surrounding the worms. Enhanced mucus secretion was recorded in the intestines of infected tench. Conclusions: The pathological changes and the inflammatory cellular response induced by the caryophyllidean monozoic tapeworm M. wageneri within the intestinal tract of an Italian population of wild tench is reported for the first time.
Type: Journal Article
URI: http://hdl.handle.net/1893/10160
DOI Link: http://dx.doi.org/10.1186/1756-3305-4-225
Rights: Publisher is open-access. Open access publishing allows free access to and distribution of published articles where the author retains copyright of their work by employing a Creative Commons attribution licence(http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Affiliation: University of Ferrara
University of Ferrara
University of Ferrara
University of Ferrara
University of Perugia
University of Stirling
Aquaculture

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