Please use this identifier to cite or link to this item:
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Masculinization of genetic female Nile tilapia (Oreochromis niloticus) by dietary administration of an aromatase inhibitor during sexual differentiation
Authors: Kwon, Joon Yeong
Haghpanah, Vahid
Kogson-Hurtado, Luz Mary
McAndrew, Brendan
Penman, David
Contact Email:
Issue Date: 15-Jun-2000
Publisher: Wiley-Blackwell
Citation: Kwon JY, Haghpanah V, Kogson-Hurtado LM, McAndrew B & Penman D (2000) Masculinization of genetic female Nile tilapia (Oreochromis niloticus) by dietary administration of an aromatase inhibitor during sexual differentiation, Journal of Experimental Zoology Part A: Ecological Genetics and Physiology, 287 (1), pp. 46-53.
Abstract: A series of experiments was carried out in which genetically female Nile tilapia (Oreochromis niloticus) fry were treated with Fadrozole, a nonsteroidal aromatase inhibitor (AI), in the diet during the period of sexual differentiation. Batches of tilapia fry treated with AI during the first 30 days following yolk-sac resorption (7-37 days post hatch, dph) showed a dose-dependent increase in the percentage of males from 0 to 200 mg · kg-1. The percentage of males remained approximately constant (92.5-96.0%) from 200 to 500 mg · kg-1. Any continuous 2- or 3-week treatment with 500 mg · kg-1 AI in this 4-week period successfully masculinized the majority of the treated fish (greater than 80%). Treatments of 1 week duration revealed that the most sensitive time to AI lies in the first week (between 7 and 14 dph). Progeny testing of males from AI-treated groups gave results indicating that these were XX males, as expected. These experiments strongly implicate aromatase activity as a key factor in sexual differentiation in the Nile tilapia.
Type: Journal Article
DOI Link:<46::AID-JEZ6>3.0.CO;2-X
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: University of Stirling
University of Stirling
University of Stirling

Files in This Item:
File Description SizeFormat 
kwonetal_JEZA_2000.pdf116.14 kBAdobe PDFUnder Embargo until 31/12/2999     Request a copy

Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependant on the depositor still being contactable at their original email address.

This item is protected by original copyright

Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact providing details and we will remove the Work from public display in STORRE and investigate your claim.